OBJECTIVE: To explore how factors such as major depressive disorder (MDD) and trauma history, including the presence of childhood abuse, influence diverse clinical outcomes such as severity and functioning in a sample with posttraumatic stress disorder (PTSD). METHOD: In this study, 200 men and women seeking treatment for chronic PTSD in a clinical trial were assessed for trauma history and MDD and compared on symptom severity, psychosocial functioning, dissociation, treatment history, and extent of diagnostic co-occurrence. RESULTS: Overall, childhood abuse did not consistently predict clinical severity. However, co-occurring MDD, and to a lesser extent a high level of trauma exposure, did predict greater severity, worse functioning, greater dissociation, more extensive treatment history, and additional co-occurring disorders. CONCLUSION: These findings suggest that presence of co-occurring depression may be a more critical marker of severity and impairment than history of childhood abuse or repeated trauma exposure. Furthermore, they emphasize the importance of assessing MDD and its effect on treatment seeking and treatment response for those with PTSD.
OBJECTIVE: To explore how factors such as major depressive disorder (MDD) and trauma history, including the presence of childhood abuse, influence diverse clinical outcomes such as severity and functioning in a sample with posttraumatic stress disorder (PTSD). METHOD: In this study, 200 men and women seeking treatment for chronic PTSD in a clinical trial were assessed for trauma history and MDD and compared on symptom severity, psychosocial functioning, dissociation, treatment history, and extent of diagnostic co-occurrence. RESULTS: Overall, childhood abuse did not consistently predict clinical severity. However, co-occurring MDD, and to a lesser extent a high level of trauma exposure, did predict greater severity, worse functioning, greater dissociation, more extensive treatment history, and additional co-occurring disorders. CONCLUSION: These findings suggest that presence of co-occurring depression may be a more critical marker of severity and impairment than history of childhood abuse or repeated trauma exposure. Furthermore, they emphasize the importance of assessing MDD and its effect on treatment seeking and treatment response for those with PTSD.
Authors: Edna B Foa; Elizabeth A Hembree; Shawn P Cahill; Sheila A M Rauch; David S Riggs; Norah C Feeny; Elna Yadin Journal: J Consult Clin Psychol Date: 2005-10
Authors: Bonnie L Green; Janice L Krupnick; Joyce Chung; Juned Siddique; Elizabeth D Krause; Dennis Revicki; Lori Frank; Jeanne Miranda Journal: J Clin Psychol Date: 2006-07
Authors: Paula P Schnurr; Matthew J Friedman; Charles C Engel; Edna B Foa; M Tracie Shea; Bruce K Chow; Patricia A Resick; Veronica Thurston; Susan M Orsillo; Rodney Haug; Carole Turner; Nancy Bernardy Journal: JAMA Date: 2007-02-28 Impact factor: 56.272
Authors: Jordan A Booker; Matthew E Graci; Lauren A Hudak; Tanja Jovanovic; Barbara O Rothbaum; Kerry J Ressler; Robyn Fivush; Jennifer Stevens Journal: J Trauma Stress Date: 2018-04-06
Authors: Julianne C Flanagan; Lauren M Sippel; Megan M Moran Santa Maria; Karen J Hartwell; Kathleen T Brady; Jane E Joseph Journal: Eur J Psychotraumatol Date: 2019-05-07