Literature DB >> 25896244

Experimental Curative Fluorescence-guided Surgery of Highly Invasive Glioblastoma Multiforme Selectively Labeled With a Killer-reporter Adenovirus.

Shuya Yano1, Shinji Miwa2, Hiroyuki Kishimoto3, Makoto Toneri2, Yukihiko Hiroshima2, Mako Yamamoto2, Michael Bouvet4, Yasuo Urata5, Hiroshi Tazawa6, Shunsuke Kagawa3, Toshiyoshi Fujiwara3, Robert M Hoffman7.   

Abstract

Fluorescence-guided surgery (FGS) of cancer is an area of intense current interest. However, although benefits have been demonstrated with FGS, curative strategies need to be developed. Glioblastoma multiforme (GBM) is one of the most invasive of cancers and is not totally resectable using standard bright-light surgery (BLS) or current FGS strategies. We report here a curative strategy for FGS of GBM. In this study, telomerase-dependent adenovirus OBP-401 infection brightly and selectively labeled GBM with green fluorescent protein (GFP) for FGS in orthotopic nude mouse models. OBP-401-based FGS enabled curative resection of GBM without recurrence for at least 150 days, compared to less than 30 days with BLS.

Entities:  

Mesh：

Substances：

Year:  2015        PMID： 25896244      PMCID： PMC4817790          DOI： 10.1038/mt.2015.63

Source DB:  PubMed          Journal:  Mol Ther        ISSN： 1525-0016            Impact factor:   11.454


  51 in total

1.  Selective metastatic tumor labeling with green fluorescent protein and killing by systemic administration of telomerase-dependent adenoviruses.

Authors:  Hiroyuki Kishimoto; Yasuo Urata; Noriaki Tanaka; Toshiyoshi Fujiwara; Robert M Hoffman
Journal:  Mol Cancer Ther       Date:  2009-11-03       Impact factor: 6.261

2.  Tumor-specific fluorescence antibody imaging enables accurate staging laparoscopy in an orthotopic model of pancreatic cancer.

Authors:  Hop S Tran Cao; Sharmeela Kaushal; Cristina A Metildi; Rhiana S Menen; Claudia Lee; Cynthia S Snyder; Karen Messer; Minya Pu; George A Luiken; Mark A Talamini; Robert M Hoffman; Michael Bouvet
Journal:  Hepatogastroenterology       Date:  2012-09

3.  Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial.

Authors:  Walter Stummer; Uwe Pichlmeier; Thomas Meinel; Otmar Dieter Wiestler; Friedhelm Zanella; Hans-Jürgen Reulen
Journal:  Lancet Oncol       Date:  2006-05       Impact factor: 41.316

4.  Glowing tumors make for better detection and resection.

Authors:  Michael Bouvet; Robert M Hoffman
Journal:  Sci Transl Med       Date:  2011-11-23       Impact factor: 17.956

5.  Correlation of clinical features and telomerase activity in human gliomas.

Authors:  F Huang; H Kanno; I Yamamoto; Y Lin; Y Kubota
Journal:  J Neurooncol       Date:  1999-06       Impact factor: 4.130

Review 6.  The WHO classification of tumors of the nervous system.

Authors:  Paul Kleihues; David N Louis; Bernd W Scheithauer; Lucy B Rorke; Guido Reifenberger; Peter C Burger; Webster K Cavenee
Journal:  J Neuropathol Exp Neurol       Date:  2002-03       Impact factor: 3.685

7.  Visualization of intrathoracically disseminated solid tumors in mice with optical imaging by telomerase-specific amplification of a transferred green fluorescent protein gene.

Authors:  Tatsuo Umeoka; Takeshi Kawashima; Shunsuke Kagawa; Fuminori Teraishi; Masaki Taki; Masahiko Nishizaki; Satoru Kyo; Katsuyuki Nagai; Yasuo Urata; Noriaki Tanaka; Toshiyoshi Fujiwara
Journal:  Cancer Res       Date:  2004-09-01       Impact factor: 12.701

8.  Hand-held high-resolution fluorescence imaging system for fluorescence-guided surgery of patient and cell-line pancreatic tumors growing orthotopically in nude mice.

Authors:  Yukihiko Hiroshima; Ali Maawy; Sho Sato; Takashi Murakami; Fuminari Uehara; Shinji Miwa; Shuya Yano; Masashi Momiyama; Takashi Chishima; Kuniya Tanaka; Michael Bouvet; Itaru Endo; Robert M Hoffman
Journal:  J Surg Res       Date:  2013-11-19       Impact factor: 2.192

9.  Metastatic recurrence in a pancreatic cancer patient derived orthotopic xenograft (PDOX) nude mouse model is inhibited by neoadjuvant chemotherapy in combination with fluorescence-guided surgery with an anti-CA 19-9-conjugated fluorophore.

Authors:  Yukihiko Hiroshima; Ali Maawy; Yong Zhang; Takashi Murakami; Masashi Momiyama; Ryutaro Mori; Ryusei Matsuyama; Matthew H G Katz; Jason B Fleming; Takashi Chishima; Kuniya Tanaka; Yasushi Ichikawa; Itaru Endo; Robert M Hoffman; Michael Bouvet
Journal:  PLoS One       Date:  2014-12-02       Impact factor: 3.240

10.  Improving the extent of malignant glioma resection by dual intraoperative visualization approach.

Authors:  Ilker Y Eyüpoglu; Nirjhar Hore; Nic E Savaskan; Peter Grummich; Karl Roessler; Michael Buchfelder; Oliver Ganslandt
Journal:  PLoS One       Date:  2012-09-26       Impact factor: 3.240
View more
  22 in total

1.  Near-Infrared Photochemoimmunotherapy by Photoactivatable Bifunctional Antibody-Drug Conjugates Targeting Human Epidermal Growth Factor Receptor 2 Positive Cancer.

Authors:  Kimihiro Ito; Makoto Mitsunaga; Takashi Nishimura; Masayuki Saruta; Takeo Iwamoto; Hisataka Kobayashi; Hisao Tajiri
Journal:  Bioconjug Chem       Date:  2017-04-26       Impact factor: 4.774

2.  Shedding New Light on the Use of Imaging Technology for Glioblastoma Tumor Resection.

Authors:  John Nemunaitis; Neil Senzer
Journal:  Mol Ther       Date:  2015-07       Impact factor: 11.454

3.  Eradication of melanoma in vitro and in vivo via targeting with a Killer-Red-containing telomerase-dependent adenovirus.

Authors:  Kiyoto Takehara; Shuya Yano; Hiroshi Tazawa; Hiroyuki Kishimoto; Nobuhiro Narii; Hiroyuki Mizuguchi; Yasuo Urata; Shunsuke Kagawa; Toshiyoshi Fujiwara; Robert M Hoffman
Journal:  Cell Cycle       Date:  2017-01-05       Impact factor: 4.534

4.  Effective fluorescence-guided surgery of liver metastasis using a fluorescent anti-CEA antibody.

Authors:  Yukihiko Hiroshima; Thinzar M Lwin; Takashi Murakami; Ali A Mawy; Tanaka Kuniya; Takashi Chishima; Itaru Endo; Bryan M Clary; Robert M Hoffman; Michael Bouvet
Journal:  J Surg Oncol       Date:  2016-10-03       Impact factor: 3.454

5.  Tumor-Specific Labeling of Pancreatic Cancer Using a Humanized Anti-CEA Antibody Conjugated to a Near-Infrared Fluorophore.

Authors:  Thinzar M Lwin; Takashi Murakami; Kentaro Miyake; Paul J Yazaki; John E Shivley; Robert M Hoffman; Michael Bouvet
Journal:  Ann Surg Oncol       Date:  2018-01-25       Impact factor: 5.344

Review 6.  Advantages of patient-derived orthotopic mouse models and genetic reporters for developing fluorescence-guided surgery.

Authors:  Thinzar M Lwin; Robert M Hoffman; Michael Bouvet
Journal:  J Surg Oncol       Date:  2018-08-06       Impact factor: 3.454

Review 7.  Current status and future perspectives of fluorescence-guided surgery for cancer.

Authors:  Jonathan C DeLong; Robert M Hoffman; Michael Bouvet
Journal:  Expert Rev Anticancer Ther       Date:  2015-12-07       Impact factor: 4.512

8.  Role of Fluorophore Charge on the In Vivo Optical Imaging Properties of Near-Infrared Cyanine Dye/Monoclonal Antibody Conjugates.

Authors:  Kazuhide Sato; Alexander P Gorka; Tadanobu Nagaya; Megan S Michie; Roger R Nani; Yuko Nakamura; Vince L Coble; Olga V Vasalatiy; Rolf E Swenson; Peter L Choyke; Martin J Schnermann; Hisataka Kobayashi
Journal:  Bioconjug Chem       Date:  2015-10-23       Impact factor: 4.774

9.  Fluorescence-Guided Surgery of Liver Metastasis in Orthotopic Nude-Mouse Models.

Authors:  Takashi Murakami; Yukihiko Hiroshima; Yong Zhang; Takashi Chishima; Kuniya Tanaka; Michael Bouvet; Itaru Endo; Robert M Hoffman
Journal:  PLoS One       Date:  2015-10-01       Impact factor: 3.240

10.  Precise navigation surgery of tumours in the lung in mouse models enabled by in situ fluorescence labelling with a killer-reporter adenovirus.

Authors:  Shuya Yano; Yong Zhang; Shinji Miwa; Hiroyuki Kishimoto; Yasuo Urata; Michael Bouvet; Shunsuke Kagawa; Toshiyoshi Fujiwara; Robert M Hoffman
Journal:  BMJ Open Respir Res       Date:  2015-09-07
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.