| Literature DB >> 30080930 |
Thinzar M Lwin1, Robert M Hoffman1,2, Michael Bouvet1,3.
Abstract
Fluorescence-guided surgery can enhance the surgeon's ability to achieve a complete oncologic resection. There are a number of tumor-specific probes being developed with many preclinical mouse models to evaluate their efficacy. The current review discusses the different preclinical mouse models in the setting of probe evaluation and highlights the advantages of patient-derived orthotopic xenografts (PDOX) mouse models and genetic reporters to develop fluorescence-guided surgery.Entities:
Keywords: fluorescence-guided surgery (FGS); genetic reporters; patient-derived orthotopic xenografts (PDOX); preclinical mouse models; surgical orthotopic implantation (SOI)
Mesh:
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Year: 2018 PMID: 30080930 PMCID: PMC6146062 DOI: 10.1002/jso.25150
Source DB: PubMed Journal: J Surg Oncol ISSN: 0022-4790 Impact factor: 3.454