| Literature DB >> 25892496 |
Pasquale Patrizio1, Alberto Vaiarelli2, Paolo E Levi Setti3, Kyle J Tobler4, Gon Shoham5, Milton Leong6, Zeev Shoham7.
Abstract
Poor responders represent a significant percentage of couples treated in IVF units (10-24%), but the standard definition of poor responders remains uncertain and consequently optimal treatment options remain subjective and not evidence-based. In an attempt to provide uniformity on the definition, diagnosis and treatment of poor responders, a worldwide survey was conducted asking IVF professionals a set of questions on this complex topic. The survey was posted on www.IVF-worldwide.com, the largest and most comprehensive IVF-focused website for physicians and embryologists. A total of 196 centres replied, forming a panel of IVF units with a median of 400 cycles per year. The present study shows that the definition of poor responders is still subjective, and many practices do not use evidence-based treatment for this category of patients. Our hope is that by leveraging the great potential of the internet, future studies may provide immediate large-scale sampling to standardize both poor responder definition and treatment options.Entities:
Keywords: IVF; decreased ovarian function; management; ovarian stimulation; poor responder; survey
Mesh：
Year: 2015 PMID： 25892496 DOI： 10.1016/j.rbmo.2015.03.002
Source DB: PubMed Journal: Reprod Biomed Online ISSN： 1472-6483 Impact factor: 3.828