Literature DB >> 25891933

Injuries from seizures are a serious, persistent problem in childhood onset epilepsy: a population-based study.

Carol Camfield1, Peter Camfield2.   

Abstract

PURPOSE: Document the frequency, types and risk factors for injuries caused by seizures for people with childhood onset epilepsy.
METHOD: We contacted patients with all types of epilepsy except childhood absence from the Nova Scotia Childhood Epilepsy population-based cohort. Seizure onset was between 1977 and 1985. Patients and parents were asked about serious injuries resulting from a seizure, defined as severe enough for an urgent physician or dentist visit.
RESULTS: Of 595 eligible patients, we contacted 472 (79%). During an average follow up of 23.9 ± 8 years, 52 (11%) experienced ≥1 serious injury for a total of 81 injuries. Of all injuries, 24 (30%) were lacerations requiring sutures, 15 (19%) fractures, 11 (14%) broken teeth, 8 (10%) concussions, 4 (5%) burns, and 20 (25%) other. "Other" included 1 fatal drowning, 2 near-drownings, 3 shoulder dislocations and 1 severe eye injury. Four injuries occurred with the first seizure; all others after a long gap from seizure onset (range 1.5-30 years). Injuries occurred in all epilepsy syndromes, most commonly with symptomatic generalized epilepsy (17% vs. 11% p = 0.03) and intractable epilepsy (28% vs. 8% p<0.0001). Most injuries occurred during normal daily activities and were judged not to be easily preventable.
CONCLUSIONS: During ∼24 years of follow up 1 out of 10 patients with childhood onset epilepsy had a serious injury as the result of a seizure. Most injuries occurred years after the initial diagnosis and were more common when seizures were more frequent. The only practical solution to injury prevention is better seizure control.
Copyright © 2015 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Accidents; Childhood; Epilepsy; Injury; Population-based

Mesh:

Year:  2015        PMID: 25891933     DOI: 10.1016/j.seizure.2015.02.031

Source DB:  PubMed          Journal:  Seizure        ISSN: 1059-1311            Impact factor:   3.184


  10 in total

Review 1.  Association of Child Neurology-Indian Epilepsy Society Consensus Document on Parental Counseling of Children with Epilepsy.

Authors:  Kavita Srivastava; Rachna Sehgal; Ramesh Konanki; Ridhimaa Jain; Suvasini Sharma; Rekha Mittal; Anaita Hedge; Anju Aggarwal; Arijit Chattopadhyay; Bijoy Patra; Jaya Shankar Kaushik; Lokesh Lingappa; Naveen Sankhyan; Puja Kapoor; Pratibha Singhi; Satinder Aneja; Sheffali Gulati; Sujata Kanhere; Surekha Rajadhyakshya; Veena Kalra; Vineet Bhushan Gupta; Vrajesh Udani; Yeeshu Sudan; Man Mohan Mehendiratta; Manjari Tripathi; G T Subhash; Bhavneet Bharti; Srinivas Rao; Munawwar Naseem; Snehashish Mukherjee; Priya Jain; Mehreen Khosla; Kavita Shanbagh; Deepa Jain; Sumeet Mansingh; Dhaneshwar Yadav; Chetan Singh; Sunita Raina; Sapna Srivastava; Leena Ahuja; Rashmi Kumar; K P Vinayan; Rakesh Jain; Satish Jain; Devendra Mishra
Journal:  Indian J Pediatr       Date:  2019-06-08       Impact factor: 1.967

2.  Antiepileptic Drug Treatment Outcomes and Seizure-Related Injuries Among Adult Patients with Epilepsy in a Tertiary Care Hospital in Ethiopia.

Authors:  Beshir Bedru Nasir; Yared Mamushet Yifru; Ephrem Engidawork; Meron Awraris Gebrewold; Minyahil Alebachew Woldu; Alemseged Beyene Berha
Journal:  Patient Relat Outcome Meas       Date:  2020-04-21

3.  The Burden of Severely Drug-Refractory Epilepsy: A Comparative Longitudinal Evaluation of Mortality, Morbidity, Resource Use, and Cost Using German Health Insurance Data.

Authors:  Adam Strzelczyk; Claudia Griebel; Wolfram Lux; Felix Rosenow; Jens-Peter Reese
Journal:  Front Neurol       Date:  2017-12-22       Impact factor: 4.003

4.  Seizure related injuries - Frequent injury patterns, hospitalization and therapeutic aspects.

Authors:  Nils Mühlenfeld; Philipp Störmann; Ingo Marzi; Felix Rosenow; Adam Strzelczyk; René D Verboket; Laurent M Willems
Journal:  Chin J Traumatol       Date:  2021-10-15

5.  Characteristics of people with epilepsy in three Eastern African countries - a pooled analysis.

Authors:  Dominik Stelzle; Joyce Kaducu; Veronika Schmidt; Tamara M Welte; Bernard J Ngowi; William Matuja; Gabrielle Escheu; Peter Hauke; Vivien Richter; Emilio Ovuga; Bettina Pfausler; Erich Schmutzhard; Action Amos; Wendy Harrison; Luise Keller; Andrea S Winkler
Journal:  BMC Neurol       Date:  2022-08-26       Impact factor: 2.903

6.  Medicine possession ratio as proxy for adherence to antiepileptic drugs: prevalence, associations, and cost implications.

Authors:  Karen Jacobs; Marlene Julyan; Martie S Lubbe; Johanita R Burger; Marike Cockeran
Journal:  Patient Prefer Adherence       Date:  2016-04-12       Impact factor: 2.711

7.  Seizure-Related Injuries among People with Epilepsy at the Outpatient Department of the University of Gondar Hospital, Northwest Ethiopia: Cross-Sectional Institutional-Based Study.

Authors:  Berhanu Boru Bifftu; Bewket Tadesse Tiruneh; Mengistu Mekonnen Kelkay; Nestanet Habte Bayu; Abebe Woldesellassie Tewolde; Wubet Worku Takele; Mehammed Adem Getnet; Abere Woretaw Azagew
Journal:  Neurol Res Int       Date:  2017-12-11

8.  Incidence, Risk Factors and Consequences of Epilepsy-Related Injuries and Accidents: A Retrospective, Single Center Study.

Authors:  Laurent M Willems; Nina Watermann; Saskia Richter; Lara Kay; Anke M Hermsen; Susanne Knake; Felix Rosenow; Adam Strzelczyk
Journal:  Front Neurol       Date:  2018-06-15       Impact factor: 4.003

9.  Risk incidence of fractures and injuries: a multicenter video-EEG study of 626 generalized convulsive seizures.

Authors:  Katharina Frey; Johann Philipp Zöllner; Susanne Knake; Yulia Oganian; Lara Kay; Katharina Mahr; Fee Keil; Laurent M Willems; Katja Menzler; Sebastian Bauer; Susanne Schubert-Bast; Felix Rosenow; Adam Strzelczyk
Journal:  J Neurol       Date:  2020-07-10       Impact factor: 4.849

10.  [Inpatient treatment costs, cost-driving factors and potential reimbursement problems due to epileptic seizure-related injuries and fractures].

Authors:  René D Verboket; Nils Mühlenfeld; Jasmina Sterz; Philipp Störmann; Ingo Marzi; Yunus Balcik; Felix Rosenow; Adam Strzelczyk; Laurent M Willems
Journal:  Chirurg       Date:  2021-04       Impact factor: 0.955

  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.