| Literature DB >> 25891828 |
Nicola Tambasco1, Pasquale Nigro2, Michele Romoli2, Simone Simoni2, Lucilla Parnetti2, Paolo Calabresi3.
Abstract
Magnetic resonance imaging is the most used technique of neuroimaging. Using recent advances in magnetic resonance application it is possible to investigate several changes in neurodegenerative disease. Among different techniques, magnetization-transfer imaging (MTI), a magnetic resonance acquisition protocol assessing the magnetization exchange between protons bound to water and those bound to macromolecules, is able to identify microstructural brain tissue changes peculiar of neurodegenerative diseases. This review provides a report on the MTI technique and its use in the dementia disorders, Huntington's disease and parkinsonisms, comprehensive of the predictive values of MTI in the identification of early-phase disease.Entities:
Keywords: Dementia; Huntington's disease; MRI; Magnetic resonance imaging; Magnetization transfer; Parkinson's disease
Mesh:
Year: 2015 PMID: 25891828 DOI: 10.1016/j.jns.2015.03.025
Source DB: PubMed Journal: J Neurol Sci ISSN: 0022-510X Impact factor: 3.181