Nicolien T van Ravesteyn1, Lisanne van Lier2, Clyde B Schechter3, Donatus U Ekwueme4, Janet Royalty4, Jacqueline W Miller4, Aimee M Near5, Kathleen A Cronin6, Eveline A M Heijnsdijk7, Jeanne S Mandelblatt5, Harry J de Koning7. 1. Department of Public Health, Erasmus MC, University Medical Center, Rotterdam. Electronic address: n.vanravesteyn@erasmusmc.nl. 2. Department of Public Health, Erasmus MC, University Medical Center, Rotterdam; Department of General Practice and Elderly Care Medicine, VU University Medical Center, Amsterdam, the Netherlands. 3. Departments of Family & Social Medicine and Epidemiology & Population Health, Albert Einstein School of Medicine, Bronx, New York. 4. CDC, Atlanta, Georgia. 5. Department of Oncology, Georgetown University, Lombardi Comprehensive Cancer Center, Washington, District of Columbia. 6. Statistical Research and Application Branch, Division of Cancer Control and Population Sciences, National Cancer Institute, NIH, Bethesda, Maryland. 7. Department of Public Health, Erasmus MC, University Medical Center, Rotterdam.
Abstract
INTRODUCTION: The National Breast and Cervical Cancer Early Detection Program (NBCCEDP) provides mammograms and diagnostic services for low-income, uninsured women aged 40-64 years. Mammography facilities within the NBCCEDP gradually shifted from plain-film to digital mammography. The purpose of this study is to assess the impact of replacing film with digital mammography on health effects (deaths averted, life-years gained [LYG]); costs (for screening and diagnostics); and number of women reached. METHODS: NBCCEDP 2010 data and data representative of the program's target population were used in two established microsimulation models. Models simulated observed screening behavior including different screening intervals (annual, biennial, irregular) and starting ages (40, 50 years) for white, black, and Hispanic women. Model runs were performed in 2012. RESULTS: The models predicted 8.0-8.3 LYG per 1,000 film screens for black women, 5.9-7.5 for white women, and 4.0-4.5 for Hispanic women. For all race/ethnicity groups, digital mammography had more LYG than film mammography (2%-4%), but had higher costs (34%-35%). Assuming a fixed budget, 25%-26% fewer women could be served, resulting in 22%-24% fewer LYG if all mammograms were converted to digital. The loss in LYG could be reversed to an 8%-13% increase by only including biennial screening. CONCLUSIONS: Digital could result in slightly more LYG than film mammography. However, with a fixed budget, fewer women may be served with fewer LYG. Changes in the program, such as only including biennial screening, will increase LYG/screen and could offset the potential decrease in LYG when shifting to digital mammography.
INTRODUCTION: The National Breast and Cervical Cancer Early Detection Program (NBCCEDP) provides mammograms and diagnostic services for low-income, uninsured women aged 40-64 years. Mammography facilities within the NBCCEDP gradually shifted from plain-film to digital mammography. The purpose of this study is to assess the impact of replacing film with digital mammography on health effects (deaths averted, life-years gained [LYG]); costs (for screening and diagnostics); and number of women reached. METHODS: NBCCEDP 2010 data and data representative of the program's target population were used in two established microsimulation models. Models simulated observed screening behavior including different screening intervals (annual, biennial, irregular) and starting ages (40, 50 years) for white, black, and Hispanic women. Model runs were performed in 2012. RESULTS: The models predicted 8.0-8.3 LYG per 1,000 film screens for black women, 5.9-7.5 for white women, and 4.0-4.5 for Hispanic women. For all race/ethnicity groups, digital mammography had more LYG than film mammography (2%-4%), but had higher costs (34%-35%). Assuming a fixed budget, 25%-26% fewer women could be served, resulting in 22%-24% fewer LYG if all mammograms were converted to digital. The loss in LYG could be reversed to an 8%-13% increase by only including biennial screening. CONCLUSIONS: Digital could result in slightly more LYG than film mammography. However, with a fixed budget, fewer women may be served with fewer LYG. Changes in the program, such as only including biennial screening, will increase LYG/screen and could offset the potential decrease in LYG when shifting to digital mammography.
Authors: Solveig Hofvind; Per Skaane; Joann G Elmore; Sofie Sebuødegård; Solveig Roth Hoff; Christoph I Lee Journal: Radiology Date: 2014-04-01 Impact factor: 11.105
Authors: Nicolien T van Ravesteyn; Clyde B Schechter; Aimee M Near; Eveline A M Heijnsdijk; Michael A Stoto; Gerrit Draisma; Harry J de Koning; Jeanne S Mandelblatt Journal: Cancer Epidemiol Biomarkers Prev Date: 2010-11-30 Impact factor: 4.254
Authors: Lisa C Richardson; Janet Royalty; William Howe; William Helsel; William Kammerer; Vicki B Benard Journal: Am J Public Health Date: 2009-12-17 Impact factor: 9.308
Authors: Rebecca Smith-Bindman; Philip W Chu; Diana L Miglioretti; Edward A Sickles; Roger Blanks; Rachel Ballard-Barbash; Janet K Bobo; Nancy C Lee; Matthew G Wallis; Julietta Patnick; Karla Kerlikowske Journal: JAMA Date: 2003-10-22 Impact factor: 56.272
Authors: Jaya S Khushalani; Donatus U Ekwueme; Thomas B Richards; Susan A Sabatino; Gery P Guy; Yuanhui Zhang; Florence Tangka Journal: J Womens Health (Larchmt) Date: 2019-10-15 Impact factor: 2.681
Authors: Oguzhan Alagoz; Donald A Berry; Harry J de Koning; Eric J Feuer; Sandra J Lee; Sylvia K Plevritis; Clyde B Schechter; Natasha K Stout; Amy Trentham-Dietz; Jeanne S Mandelblatt Journal: Med Decis Making Date: 2018-04 Impact factor: 2.583
Authors: Clyde B Schechter; Aimee M Near; Jinani Jayasekera; Young Chandler; Jeanne S Mandelblatt Journal: Med Decis Making Date: 2018-04 Impact factor: 2.583
Authors: Amy Trentham-Dietz; Oguzhan Alagoz; Christina Chapman; Xuelin Huang; Jinani Jayasekera; Nicolien T van Ravesteyn; Sandra J Lee; Clyde B Schechter; Jennifer M Yeh; Sylvia K Plevritis; Jeanne S Mandelblatt Journal: PLoS Comput Biol Date: 2021-06-17 Impact factor: 4.475