Samrat Yeramaneni1, Kim N Dietrich2, Kimberly Yolton3, Patrick J Parsons4, Kenneth M Aldous4, Erin N Haynes5. 1. Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, OH; Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH. 2. Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, OH. 3. Division of General and Community Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH. 4. Division of Environmental Health Sciences, Wadsworth Center, New York State Department of Health, Albany, NY; Department of Environmental Health Sciences, School of Public Health, University at Albany, Albany, NY. 5. Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, OH. Electronic address: erin.haynes@uc.edu.
Abstract
OBJECTIVE: To investigate the relationship between secondhand tobacco smoke (SHS) exposure and neuromotor function in children. STUDY DESIGN: We studied 404 children aged 7-9 years who were exposed to SHS and other environmental neurotoxicants. Parents reported smoking habits, and serum cotinine levels were measured in children to determine SHS exposure. The Halstead-Reitan Finger Oscillation Test, Purdue Grooved Pegboard Test-Kiddie version, and Bruininks-Oseretsky Test of Motor Proficiency 2-Short Form were used to assess neuromotor function. Multivariable regression models that accounted for potential confounders were used to evaluate the associations. RESULTS: Approximately 50% of the children were exposed to SHS based on serum cotinine measures. Exposure to SHS was significantly associated with motor impairment in children, including diminished visuomotor coordination (P = .01), fine motor integration (P = .01), balance (P = .02), and strength (P = .04) after adjusting for exposures to lead and manganese, age, sex, body mass index, measures of parental cognitive abilities, parental education, and quality of home environment. CONCLUSION: SHS is a neurotoxicant that may be associated with impaired childhood neuromotor function.
OBJECTIVE: To investigate the relationship between secondhand tobacco smoke (SHS) exposure and neuromotor function in children. STUDY DESIGN: We studied 404 children aged 7-9 years who were exposed to SHS and other environmental neurotoxicants. Parents reported smoking habits, and serum cotinine levels were measured in children to determine SHS exposure. The Halstead-Reitan Finger Oscillation Test, Purdue Grooved Pegboard Test-Kiddie version, and Bruininks-Oseretsky Test of Motor Proficiency 2-Short Form were used to assess neuromotor function. Multivariable regression models that accounted for potential confounders were used to evaluate the associations. RESULTS: Approximately 50% of the children were exposed to SHS based on serum cotinine measures. Exposure to SHS was significantly associated with motor impairment in children, including diminished visuomotor coordination (P = .01), fine motor integration (P = .01), balance (P = .02), and strength (P = .04) after adjusting for exposures to lead and manganese, age, sex, body mass index, measures of parental cognitive abilities, parental education, and quality of home environment. CONCLUSION:SHS is a neurotoxicant that may be associated with impaired childhood neuromotor function.
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