Literature DB >> 25881938

Developing medicines that mimic the natural successes of the human genome: lessons from NPC1L1, HMGCR, PCSK9, APOC3, and CETP.

Sekar Kathiresan1.   

Abstract

Entities:  

Keywords:  cholesterol; coronary disease; genetics; genetic association studies; human genome; medical; triglycerides

Mesh：

Substances：

Year:  2015        PMID： 25881938     DOI： 10.1016/j.jacc.2015.02.049

Source DB:  PubMed          Journal:  J Am Coll Cardiol        ISSN： 0735-1097            Impact factor:   24.094


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  15 in total

Review 1.  Human gene essentiality.

Authors:  István Bartha; Julia di Iulio; J Craig Venter; Amalio Telenti
Journal:  Nat Rev Genet       Date:  2017-10-30       Impact factor: 53.242

2.  A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels.

Authors:  Sumeet A Khetarpal; Xuemei Zeng; John S Millar; Cecilia Vitali; Amritha Varshini Hanasoge Somasundara; Paolo Zanoni; James A Landro; Nicole Barucci; William J Zavadoski; Zhiyuan Sun; Hans de Haard; Ildikó V Toth; Gina M Peloso; Pradeep Natarajan; Marina Cuchel; Sissel Lund-Katz; Michael C Phillips; Alan R Tall; Sekar Kathiresan; Paul DaSilva-Jardine; Nathan A Yates; Daniel J Rader
Journal:  Nat Med       Date:  2017-08-21       Impact factor: 53.440

3.  Targeted Treatment of Individuals With Psychosis Carrying a Copy Number Variant Containing a Genomic Triplication of the Glycine Decarboxylase Gene.

Authors:  J Alexander Bodkin; Michael J Coleman; Laura J Godfrey; Claudia M B Carvalho; Charity J Morgan; Raymond F Suckow; Thea Anderson; Dost Öngür; Marc J Kaufman; Kathryn E Lewandowski; Arthur J Siegel; Elliot Waldstreicher; Christopher M Grochowski; Daniel C Javitt; Dan Rujescu; Scott Hebbring; Richard Weinshilboum; Stephanie Burgos Rodriguez; Colette Kirchhoff; Timothy Visscher; Alexander Vuckovic; Allison Fialkowski; Shane McCarthy; Dheeraj Malhotra; Jonathan Sebat; Donald C Goff; James I Hudson; James R Lupski; Joseph T Coyle; Uwe Rudolph; Deborah L Levy
Journal:  Biol Psychiatry       Date:  2019-05-09       Impact factor: 13.382

4.  Association of Rare CYP39A1 Variants With Exfoliation Syndrome Involving the Anterior Chamber of the Eye.

Authors:  Zheng Li; Zhenxun Wang; Mei Chin Lee; Matthias Zenkel; Esther Peh; Mineo Ozaki; Fotis Topouzis; Satoko Nakano; Anita Chan; Shuwen Chen; Susan E I Williams; Andrew Orr; Masakazu Nakano; Nino Kobakhidze; Tomasz Zarnowski; Alina Popa-Cherecheanu; Takanori Mizoguchi; Shin-Ichi Manabe; Ken Hayashi; Shigeyasu Kazama; Kenji Inoue; Yosai Mori; Kazunori Miyata; Kazuhisa Sugiyama; Tomomi Higashide; Etsuo Chihara; Ryuichi Ideta; Satoshi Ishiko; Akitoshi Yoshida; Kana Tokumo; Yoshiaki Kiuchi; Tsutomu Ohashi; Toshiya Sakurai; Takako Sugimoto; Hideki Chuman; Makoto Aihara; Masaru Inatani; Kazuhiko Mori; Yoko Ikeda; Morio Ueno; Daniel Gaston; Paul Rafuse; Lesya Shuba; Joseph Saunders; Marcelo Nicolela; George Chichua; Sergo Tabagari; Panayiota Founti; Kar Seng Sim; Wee Yang Meah; Hui Meng Soo; Xiao Yin Chen; Anthi Chatzikyriakidou; Christina Keskini; Theofanis Pappas; Eleftherios Anastasopoulos; Alexandros Lambropoulos; Evangelia S Panagiotou; Dimitrios G Mikropoulos; Ewa Kosior-Jarecka; Augustine Cheong; Yuanhan Li; Urszula Lukasik; Monisha E Nongpiur; Rahat Husain; Shamira A Perera; Lydia Álvarez; Montserrat García; Héctor González-Iglesias; Andrés Fernández-Vega Cueto; Luis Fernández-Vega Cueto; Federico Martinón-Torres; Antonio Salas; Çilingir Oguz; Nevbahar Tamcelik; Eray Atalay; Bilge Batu; Murat Irkec; Dilek Aktas; Burcu Kasim; Yury S Astakhov; Sergei Y Astakhov; Eugeny L Akopov; Andreas Giessl; Christian Mardin; Claus Hellerbrand; Jessica N Cooke Bailey; Robert P Igo; Jonathan L Haines; Deepak P Edward; Steffen Heegaard; Sonia Davila; Patrick Tan; Jae H Kang; Louis R Pasquale; Friedrich E Kruse; André Reis; Trevor R Carmichael; Michael Hauser; Michele Ramsay; Georg Mossböck; Nilgun Yildirim; Kei Tashiro; Anastasios G P Konstas; Miguel Coca-Prados; Jia Nee Foo; Shigeru Kinoshita; Chie Sotozono; Toshiaki Kubota; Michael Dubina; Robert Ritch; Janey L Wiggs; Francesca Pasutto; Ursula Schlötzer-Schrehardt; Ying Swan Ho; Tin Aung; Wai Leong Tam; Chiea Chuen Khor
Journal:  JAMA       Date:  2021-02-23       Impact factor: 56.272

Review 5.  The Genetics of Stress-Related Disorders: PTSD, Depression, and Anxiety Disorders.

Authors:  Jordan W Smoller
Journal:  Neuropsychopharmacology       Date:  2015-08-31       Impact factor: 7.853

Review 6.  GPIHBP1 and Plasma Triglyceride Metabolism.

Authors:  Loren G Fong; Stephen G Young; Anne P Beigneux; André Bensadoun; Monika Oberer; Haibo Jiang; Michael Ploug
Journal:  Trends Endocrinol Metab       Date:  2016-05-14       Impact factor: 12.015

Review 7.  Psychiatric genetics and the structure of psychopathology.

Authors:  Jordan W Smoller; Ole A Andreassen; Howard J Edenberg; Stephen V Faraone; Stephen J Glatt; Kenneth S Kendler
Journal:  Mol Psychiatry       Date:  2018-01-09       Impact factor: 15.992

8.  Association Between Low-Density Lipoprotein Cholesterol-Lowering Genetic Variants and Risk of Type 2 Diabetes: A Meta-analysis.

Authors:  Robert A Scott; Nicholas J Wareham; Luca A Lotta; Stephen J Sharp; Stephen Burgess; John R B Perry; Isobel D Stewart; Sara M Willems; Jian'an Luan; Eva Ardanaz; Larraitz Arriola; Beverley Balkau; Heiner Boeing; Panos Deloukas; Nita G Forouhi; Paul W Franks; Sara Grioni; Rudolf Kaaks; Timothy J Key; Carmen Navarro; Peter M Nilsson; Kim Overvad; Domenico Palli; Salvatore Panico; Jose-Ramón Quirós; Elio Riboli; Olov Rolandsson; Carlotta Sacerdote; Elena C Salamanca; Nadia Slimani; Annemieke Mw Spijkerman; Anne Tjonneland; Rosario Tumino; Daphne L van der A; Yvonne T van der Schouw; Mark I McCarthy; Inês Barroso; Stephen O'Rahilly; David B Savage; Naveed Sattar; Claudia Langenberg
Journal:  JAMA       Date:  2016-10-04       Impact factor: 56.272

9.  Harnessing publicly available genetic data to prioritize lipid modifying therapeutic targets for prevention of coronary heart disease based on dysglycemic risk.

Authors:  Vinicius Tragante; Folkert W Asselbergs; Daniel I Swerdlow; Tom M Palmer; Jason H Moore; Paul I W de Bakker; Brendan J Keating; Michael V Holmes
Journal:  Hum Genet       Date:  2016-03-05       Impact factor: 4.132

10.  APOC3 induces endothelial dysfunction through TNF-α and JAM-1.

Authors:  Yun Tao; Yisong Xiong; Huimin Wang; Shaopeng Chu; Renqian Zhong; Jianxin Wang; Guihua Wang; Xiumei Ren; Juan Yu
Journal:  Lipids Health Dis       Date:  2016-09-13       Impact factor: 3.876
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