Yoshimasa Sueda1, Naohisa Hosomi2, Miwako Tsunematsu3, Kazuhiro Takamatsu4, Eiichi Nomura5, Tsuyoshi Torii1, Toshiho Ohtsuki6, Shiro Aoki6, Tomoya Mukai6, Tomohisa Nezu6, Masayuki Kakehashi3, Masayasu Matsumoto6. 1. Department of Neurology, National Hospital Organization Kure Medical Center, Kure, Japan. 2. Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan. Electronic address: nhosomi@hiroshima-u.ac.jp. 3. Department of Health Informatics, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan. 4. Department of Neurology, Brain Attack Center Ota Memorial Hospital, Fukuyama, Japan. 5. Department of Neurology, Suiseikai Kajikawa Hospital, Hiroshima, Japan. 6. Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan.
Abstract
BACKGROUND: Predicting a day that presents a high risk for the occurrence of ischemic stroke events may enable health professionals to prepare for emergency stroke therapy more properly. We evaluated the association between meteorological conditions and the frequency of ischemic stroke events in Japanese patients. METHODS: Ischemic stroke patients (n = 299) who were treated with alteplase at 9 stroke hospitals in 3 restricted areas were examined. The daily rates of ischemic stroke events were compared with the daily mean thermo-hydrological index (THI), the atmospheric pressure, and the daily changes of these variables for the 6 days preceding an ischemic stroke event using Poisson regression analysis. RESULTS: We trisected onset days based on the THI (low-temperature, intermediate-temperature, and high-temperature), atmospheric pressure (low-pressure, intermediate-pressure, and high-pressure), changes in THI for preceding 6 days from the previous day (cooler, unchanged-temperature, and warmer), and changes in atmospheric pressure (decreased-pressure, unchanged-pressure, and increased-pressure). The frequency of ischemic stroke was significantly higher on low-temperature or high-pressure days (risk ratio, 1.398, P = .022; risk ratio, 1.374, P = .039), on warmer-temperature days, and when atmospheric pressure varied from the day before (P < .05). There were significantly lower risks for ischemic stroke events on cooler-temperature days, and higher risks were associated with a variation in atmospheric pressure 3 days before the onset from 4 days before (P < .05). CONCLUSIONS: There were higher risks for ischemic stroke events associated with low ambient temperature, high atmospheric pressure, increased temperature, and varied atmospheric pressure. Also, atmospheric pressure variation 3 days before may be associated.
BACKGROUND: Predicting a day that presents a high risk for the occurrence of ischemic stroke events may enable health professionals to prepare for emergency stroke therapy more properly. We evaluated the association between meteorological conditions and the frequency of ischemic stroke events in Japanese patients. METHODS:Ischemic strokepatients (n = 299) who were treated with alteplase at 9 stroke hospitals in 3 restricted areas were examined. The daily rates of ischemic stroke events were compared with the daily mean thermo-hydrological index (THI), the atmospheric pressure, and the daily changes of these variables for the 6 days preceding an ischemic stroke event using Poisson regression analysis. RESULTS: We trisected onset days based on the THI (low-temperature, intermediate-temperature, and high-temperature), atmospheric pressure (low-pressure, intermediate-pressure, and high-pressure), changes in THI for preceding 6 days from the previous day (cooler, unchanged-temperature, and warmer), and changes in atmospheric pressure (decreased-pressure, unchanged-pressure, and increased-pressure). The frequency of ischemic stroke was significantly higher on low-temperature or high-pressure days (risk ratio, 1.398, P = .022; risk ratio, 1.374, P = .039), on warmer-temperature days, and when atmospheric pressure varied from the day before (P < .05). There were significantly lower risks for ischemic stroke events on cooler-temperature days, and higher risks were associated with a variation in atmospheric pressure 3 days before the onset from 4 days before (P < .05). CONCLUSIONS: There were higher risks for ischemic stroke events associated with low ambient temperature, high atmospheric pressure, increased temperature, and varied atmospheric pressure. Also, atmospheric pressure variation 3 days before may be associated.
Authors: András Folyovich; Dávid Biczó; Nadim Al-Muhanna; Anna K Béres-Molnár; Ádám Fejős; Ádám Pintér; Dániel Bereczki; Antal Fischer; Károly Vadasdi; Ferenc Pintér Journal: Environ Monit Assess Date: 2015-08-02 Impact factor: 2.513
Authors: Hui Lian; Yanping Ruan; Ruijuan Liang; Xiaole Liu; Zhongjie Fan Journal: Int J Environ Res Public Health Date: 2015-07-31 Impact factor: 3.390
Authors: Philipp Bücke; Hans Henkes; Guy Arnold; Birgit Herting; Eric Jüttler; Christof Klötzsch; Alfred Lindner; Uwe Mauz; Ludwig Niehaus; Matthias Reinhard; Stefan Waibel; Thomas Horvath; Hansjörg Bäzner; Marta Aguilar Pérez Journal: Eur J Neurol Date: 2021-05-05 Impact factor: 6.288