Literature DB >> 25873083

Declining newborn intramuscular vitamin K prophylaxis predicts subsequent immunisation refusal: A retrospective cohort study.

Helen Bernhardt1, David Barker2, David M Reith2, Roland S Broadbent2, Pamela M Jackson2, Benjamin J Wheeler2.   

Abstract

AIM: Low rates of childhood immunisation are linked to outbreaks of infectious disease. Identifying and addressing barriers to immunisation may lead to improved immunisation rates. Immunisation and newborn vitamin K prophylaxis have many similarities. We aimed to investigate whether parents who decline newborn vitamin K are also more likely to decline subsequent childhood immunisations.
METHODS: We undertook a retrospective cohort study, examining the relationship between vitamin K administration and immunisation uptake by parents of babies born over a 2-year period (January 2010-December 2011) in Dunedin, New Zealand (NZ). Both written and electronic data from a single birthing unit and the NZ National Immunisation Register (NIR) were analysed to ascertain the relationship between declining newborn vitamin K prophylaxis and subsequent immunisation uptake.
RESULTS: Records for 3575 babies were examined. Ninety-two per cent of infants received intramuscular, and 5% received oral vitamin K. An increased risk ratio for non-immunisation of 14.1 (95% confidence interval 7.8-25.9) for babies whose parents declined vitamin K was identified. Receiving oral vitamin K was also associated with subsequent non-immunisation, with a risk ratio of 3.5 (95% confidence interval 1.7-7.3).
CONCLUSIONS: Parents who decline newborn vitamin K are more likely to decline immunisation for their child. These parents, as well as those that elect for oral vitamin K, are a small but easily identifiable group to whom additional education about the benefits of immunisation could be offered. This is especially pertinent at a time when there is a resurgence of immunisation preventable diseases.
© 2015 The Authors. Journal of Paediatrics and Child Health © 2015 Paediatrics and Child Health Division (Royal Australasian College of Physicians).

Entities:  

Keywords:  immunisation; neonate; prophylaxis; vaccine; vitamin K

Mesh:

Substances:

Year:  2015        PMID: 25873083     DOI: 10.1111/jpc.12887

Source DB:  PubMed          Journal:  J Paediatr Child Health        ISSN: 1034-4810            Impact factor:   1.954


  5 in total

Review 1.  Refusal of Intramuscular Vitamin K by Parents of Newborns: A Review.

Authors:  Jaspreet Loyal; Eugene D Shapiro
Journal:  Hosp Pediatr       Date:  2020-02-04

2.  Refusal of Vitamin K by Parents of Newborns: A Survey of the Better Outcomes Through Research for Newborns Network.

Authors:  Jaspreet Loyal; James A Taylor; Carrie A Phillipi; Neera K Goyal; Niramol Dhepyasuwan; Eugene D Shapiro; Eve Colson
Journal:  Acad Pediatr       Date:  2017-03-09       Impact factor: 3.107

3.  Refusal of Vitamin K by Parents of Newborns: A Qualitative Study.

Authors:  Jaspreet Loyal; Theresa R Weiss; Jessica H Cheng; Laura R Kair; Eve Colson
Journal:  Acad Pediatr       Date:  2019-04-11       Impact factor: 3.107

4.  Oral Vitamin K Prophylaxis in Newborns: A Survey of Clinician Opinions and Practices.

Authors:  Jessica H Cheng; Jaspreet Loyal; Kelly E Wood; Laura R Kair
Journal:  Hosp Pediatr       Date:  2020-01-06

Review 5.  Countering vaccine hesitancy through immunization information systems, a narrative review.

Authors:  Vincenza Gianfredi; Massimo Moretti; Pier Luigi Lopalco
Journal:  Hum Vaccin Immunother       Date:  2019-06-21       Impact factor: 3.452

  5 in total

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