Literature DB >> 31907174

Oral Vitamin K Prophylaxis in Newborns: A Survey of Clinician Opinions and Practices.

Jessica H Cheng1, Jaspreet Loyal2, Kelly E Wood3, Laura R Kair4.   

Abstract

OBJECTIVES: The majority of newborns in the United States receive intramuscular (IM) vitamin K for prophylaxis against vitamin K deficiency bleeding (VKDB). Oral vitamin K is less effective than IM vitamin K in preventing VKDB but is widely used in Europe and by some in the United States when parents refuse IM vitamin K for their newborn. Our aim was to assess the practices, opinions, and knowledge of newborn clinicians regarding oral vitamin K prophylaxis when parents refuse IM vitamin K.
METHODS: We conducted an electronic survey of newborn clinicians from 3 academic medical centers in California, Iowa, and Connecticut. Descriptive statistics and χ2 tests were performed.
RESULTS: Of 160 newborn clinicians at 3 sites, 110 (69%) completed the survey. Of respondents, 58 (53%) believed the incidence of IM vitamin K refusal is increasing and had prescribed or recommended oral vitamin K at least once. Regarding knowledge, 32 (28%) and 23 (20%) respondents did not know whether oral vitamin K decreases the risk of early- and late-onset VKDB, respectively. There were no significant differences in opinions, knowledge, or practices across institutions or practice settings (NICU, well-newborn nursery, or both) (P > .05).
CONCLUSIONS: Our study findings suggest that newborn clinicians may lack knowledge about the effectiveness of oral vitamin K in preventing VKDB. More information is needed about oral vitamin K regimens and outcomes of newborns who receive oral vitamin K.
Copyright © 2020 by the American Academy of Pediatrics.

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Year:  2020        PMID: 31907174      PMCID: PMC6986901          DOI: 10.1542/hpeds.2019-0219

Source DB:  PubMed          Journal:  Hosp Pediatr        ISSN: 2154-1671


  22 in total

1.  Observations on the prophylactic use of vitamin Kin the newborn infant.

Authors:  T J VIETTI; T P MURPHY; J A JAMES; J A PRITCHARD
Journal:  J Pediatr       Date:  1960-03       Impact factor: 4.406

2.  Rise in late onset vitamin K deficiency bleeding in young infants because of omission or refusal of prophylaxis at birth.

Authors:  Rachael Schulte; Lori C Jordan; Anna Morad; Robert P Naftel; John C Wellons; Robert Sidonio
Journal:  Pediatr Neurol       Date:  2014-02-28       Impact factor: 3.372

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Authors:  C Croucher; D Azzopardi
Journal:  BMJ       Date:  1994-04-02

Review 4.  Use of oral vitamin K for prevention of late vitamin k deficiency bleeding in neonates when injectable vitamin K is not available.

Authors:  Heather J Ipema
Journal:  Ann Pharmacother       Date:  2012-05-22       Impact factor: 3.154

Review 5.  Vitamin K deficiency bleeding (VKDB) in infancy. ISTH Pediatric/Perinatal Subcommittee. International Society on Thrombosis and Haemostasis.

Authors:  A H Sutor; R von Kries; E A Cornelissen; A W McNinch; M Andrew
Journal:  Thromb Haemost       Date:  1999-03       Impact factor: 5.249

6.  Refusal of Vitamin K by Parents of Newborns: A Qualitative Study.

Authors:  Jaspreet Loyal; Theresa R Weiss; Jessica H Cheng; Laura R Kair; Eve Colson
Journal:  Acad Pediatr       Date:  2019-04-11       Impact factor: 3.107

Review 7.  Prophylactic vitamin K for vitamin K deficiency bleeding in neonates.

Authors:  R M Puckett; M Offringa
Journal:  Cochrane Database Syst Rev       Date:  2000

8.  Factors Associated With Refusal of Intramuscular Vitamin K in Normal Newborns.

Authors:  Jaspreet Loyal; James A Taylor; Carrie A Phillipi; Neera K Goyal; Kelly E Wood; Carl Seashore; Beth King; Eve Colson; Veronika Shabanova; Eugene D Shapiro
Journal:  Pediatrics       Date:  2018-08       Impact factor: 7.124

9.  Vitamin K administration in neonates: survey of compliance with recommended practices in the Dunedin area.

Authors:  O Doran; N C Austin; B J Taylor
Journal:  N Z Med J       Date:  1995-08-25

Review 10.  Vitamin K prophylaxis for prevention of vitamin K deficiency bleeding: a systematic review.

Authors:  M J Sankar; A Chandrasekaran; P Kumar; A Thukral; R Agarwal; V K Paul
Journal:  J Perinatol       Date:  2016-05       Impact factor: 2.521

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  1 in total

1.  Physicians' Opinion and Practice of Vitamin K Administration at Birth in Romania.

Authors:  Andreea Avasiloaiei; Demetra Gabriela Socolov; Maria Stamatin; Mihaela Moscalu
Journal:  Healthcare (Basel)       Date:  2022-03-16
  1 in total

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