Literature DB >> 25870051

Lab-on-a-chip technology.

Eleanor A M Graham1.   

Abstract

The techniques and laboratory processes involved in the production of DNA profiles for forensic applications are well developed, robust, and reliable. Unfortunately, they can now also be considered too slow and expensive to be able to match the ever-increasing demands placed upon them. The most rapid DNA profiling instrumentation in current usage are capillary electrophoresis (CE) systems. CE systems have greatly enhanced visualization and analysis throughput, but are still unable to keep up with current demand. However, developments in nanobiotechnology are allowing for the production of miniature systems to decrease the time and costs involved in profile production.

Year:  2005        PMID: 25870051     DOI: 10.1385/FSMP:1:3:221

Source DB:  PubMed          Journal:  Forensic Sci Med Pathol        ISSN: 1547-769X            Impact factor:   2.007


  14 in total

1.  Single-molecule DNA amplification and analysis in an integrated microfluidic device.

Authors:  E T Lagally; I Medintz; R A Mathies
Journal:  Anal Chem       Date:  2001-02-01       Impact factor: 6.986

2.  Integrated system for rapid PCR-based DNA analysis in microfluidic devices.

Authors:  J Khandurina; T E McKnight; S C Jacobson; L C Waters; R S Foote; J M Ramsey
Journal:  Anal Chem       Date:  2000-07-01       Impact factor: 6.986

3.  Capillary-based fully integrated and automated system for nanoliter polymerase chain reaction analysis directly from cheek cells.

Authors:  Y He; Y H Zhang; E S Yeung
Journal:  J Chromatogr A       Date:  2001-07-27       Impact factor: 4.759

4.  A nanoliter rotary device for polymerase chain reaction.

Authors:  Jian Liu; Markus Enzelberger; Stephen Quake
Journal:  Electrophoresis       Date:  2002-05       Impact factor: 3.535

Review 5.  Micro total analysis system (micro-TAS) in biotechnology.

Authors:  S J Lee; S Y Lee
Journal:  Appl Microbiol Biotechnol       Date:  2004-01-09       Impact factor: 4.813

Review 6.  Forensic DNA typing by capillary electrophoresis using the ABI Prism 310 and 3100 genetic analyzers for STR analysis.

Authors:  John M Butler; Eric Buel; Federica Crivellente; Bruce R McCord
Journal:  Electrophoresis       Date:  2004-06       Impact factor: 3.535

7.  Fully integrated PCR-capillary electrophoresis microsystem for DNA analysis.

Authors:  E T Lagally; C A Emrich; R A Mathies
Journal:  Lab Chip       Date:  2001-11-21       Impact factor: 6.799

Review 8.  DNA sequencing and genotyping in miniaturized electrophoresis systems.

Authors:  Cheuk-Wai Kan; Christopher P Fredlake; Erin A S Doherty; Annelise E Barron
Journal:  Electrophoresis       Date:  2004-11       Impact factor: 3.535

9.  Rapid microvolume PCR of DNA confirmed by microchip electrophoresis.

Authors:  Yukari Hataoka; Lihua Zhang; Tetsuo Yukimasa; Yoshinobu Baba
Journal:  Anal Sci       Date:  2005-01       Impact factor: 2.081

10.  Hypervariable 'minisatellite' regions in human DNA.

Authors:  A J Jeffreys; V Wilson; S L Thein
Journal:  Nature       Date:  1985 Mar 7-13       Impact factor: 49.962

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  1 in total

1.  Disaster victim identification.

Authors:  Eleanor A M Graham
Journal:  Forensic Sci Med Pathol       Date:  2006-09       Impact factor: 2.456

  1 in total

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