David B Sarwer1, Jacqueline C Spitzer2, Thomas A Wadden2, Raymond C Rosen3, James E Mitchell4, Kathy Lancaster4, Anita Courcoulas5, William Gourash5, Nicholas J Christian6. 1. Department of Psychiatry, Center for Weight and Eating Disorders, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; Department of Surgery, Division of Plastic Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: dsarwer@mail.med.upenn.edu. 2. Department of Psychiatry, Center for Weight and Eating Disorders, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. 3. New England Research Institutes, Watertown, Massachusetts. 4. Neuropsychiatric Research Institute, and the University of North Dakota School of Medicine and Health Sciences, Fargo, North Dakota. 5. University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania. 6. Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.
Abstract
BACKGROUND: The relationship between obesity and impairments in male sexual functioning is well documented. Relatively few studies have investigated changes in sexual functioning and sex hormones in men who achieve significant weight loss with bariatric surgery. The objective of this study was to assess changes in sexual functioning, sex hormones, and relevant psychosocial constructs in men who underwent bariatric surgery. METHODS: A prospective cohort study of 32 men from the Longitudinal Assessment of Bariatric Surgery-2 (LABS) investigation who underwent a Roux-en-Y gastric bypass (median body mass index [25th percentile, 75th percentile] 45.1 [42.0, 52.2]) and completed assessments between 2006 and 2012. Bariatric surgery was performed by a LABS-certified surgeon. Sexual functioning was assessed by the International Index of Erectile Functioning (IIEF). Hormones were assessed by blood assay. Quality of life (QoL), body image, depressive symptoms and marital adjustment were assessed by questionnaire. RESULTS: Men lost, on average, (95% confidence interval) 33.3% (36.1%, 30.5%) of initial weight at postoperative year 1, 33.6% (36.8%, 30.5%) at year 2, 31.0% (34.1%, 27.9%) at year 3, and 29.4% (32.7%, 26.2%) at year 4. Participants experienced significant increases in total testosterone (P<.001) and sex hormone binding globulin (SHBG) (P<.001) through postoperative year 4. Although men reported improvements in sexual functioning after surgery, these changes did not significantly differ from baseline, with the exception of overall satisfaction at postoperative year 3 (P = .008). Participants reported significant improvements in physical domains of health-related quality of life (HRQoL), all domains of weight-related QOL, and body image, but not in the mental health domains of HRQoL or relationship satisfaction. CONCLUSIONS: Men who lost approximately one third of their weight after Roux-en-Y gastric bypass experienced significant increases in total testosterone and SHBG. They did not, however, report significant improvements in sexual functioning, relationship satisfaction, or mental health domains of HRQoL. This pattern of results differs from that of women who have undergone bariatric surgery, who reported almost uniform improvements in sexual functioning and psychosocial status.
BACKGROUND: The relationship between obesity and impairments in male sexual functioning is well documented. Relatively few studies have investigated changes in sexual functioning and sex hormones in men who achieve significant weight loss with bariatric surgery. The objective of this study was to assess changes in sexual functioning, sex hormones, and relevant psychosocial constructs in men who underwent bariatric surgery. METHODS: A prospective cohort study of 32 men from the Longitudinal Assessment of Bariatric Surgery-2 (LABS) investigation who underwent a Roux-en-Y gastric bypass (median body mass index [25th percentile, 75th percentile] 45.1 [42.0, 52.2]) and completed assessments between 2006 and 2012. Bariatric surgery was performed by a LABS-certified surgeon. Sexual functioning was assessed by the International Index of Erectile Functioning (IIEF). Hormones were assessed by blood assay. Quality of life (QoL), body image, depressive symptoms and marital adjustment were assessed by questionnaire. RESULTS:Men lost, on average, (95% confidence interval) 33.3% (36.1%, 30.5%) of initial weight at postoperative year 1, 33.6% (36.8%, 30.5%) at year 2, 31.0% (34.1%, 27.9%) at year 3, and 29.4% (32.7%, 26.2%) at year 4. Participants experienced significant increases in total testosterone (P<.001) and sex hormone binding globulin (SHBG) (P<.001) through postoperative year 4. Although men reported improvements in sexual functioning after surgery, these changes did not significantly differ from baseline, with the exception of overall satisfaction at postoperative year 3 (P = .008). Participants reported significant improvements in physical domains of health-related quality of life (HRQoL), all domains of weight-related QOL, and body image, but not in the mental health domains of HRQoL or relationship satisfaction. CONCLUSIONS:Men who lost approximately one third of their weight after Roux-en-Y gastric bypass experienced significant increases in total testosterone and SHBG. They did not, however, report significant improvements in sexual functioning, relationship satisfaction, or mental health domains of HRQoL. This pattern of results differs from that of women who have undergone bariatric surgery, who reported almost uniform improvements in sexual functioning and psychosocial status.
Authors: David B Sarwer; Rebecca J Dilks; Jacqueline C Spitzer; Robert I Berkowitz; Thomas A Wadden; Renee H Moore; Jesse L Chittams; Mary L Brandt; Mike K Chen; Anita P Courcoulas; Carroll M Harmon; Michael A Helmrath; Marc P Michalsky; Stavra A Xanthakos; Meg H Zeller; Todd M Jenkins; Thomas H Inge Journal: Obes Surg Date: 2017-12 Impact factor: 4.129
Authors: David B Sarwer; Thomas A Wadden; Jacqueline C Spitzer; James E Mitchell; Kathy Lancaster; Anita Courcoulas; William Gourash; Raymond C Rosen; Nicholas J Christian Journal: Obes Surg Date: 2018-04 Impact factor: 4.129
Authors: Yung Lee; Jerry T Dang; Noah Switzer; James Yu; Chunhong Tian; Daniel W Birch; Shahzeer Karmali Journal: Obes Surg Date: 2019-01 Impact factor: 4.129
Authors: R Apple; L R Samuels; C Fonnesbeck; D Schlundt; S Mulvaney; M Hargreaves; D Crenshaw; K A Wallston; W J Heerman Journal: Obes Sci Pract Date: 2018-07-25