T Rasamiravaka1, H S L Shaista Sheila2, T Rakotomavojaona2, A O Rakoto-Alson3, A Rasamindrakotroka2. 1. Laboratory of Training and Research in Medical Biology, 7, rue Joel-Rakotomalala - lot IIH 11 Bis Faravohitra 101, Antananarivo, Madagascar. Electronic address: travaka@yahoo.fr. 2. Laboratory of Training and Research in Medical Biology, 7, rue Joel-Rakotomalala - lot IIH 11 Bis Faravohitra 101, Antananarivo, Madagascar. 3. Department of Medical Biology, Faculty of Medicine, University of Antananarivo 101, Antananarivo, Madagascar.
Abstract
OBJECTIVES: We wanted to update the distribution of community-acquired uropathogens and to estimate their susceptibility profile to newly available antibiotics in Antananarivo (Madagascar). MATERIALS AND METHODS: We conducted a 3-year preliminary study (2011-2013) on bacteria isolated from the urine of patients at the Laboratory of Training and Research in Medical Biology (Antananarivo). RESULTS: Three hundred and fifty-seven pathogens were isolated: 234 (65.55%) Gram-negative bacilli and 123 (34.45%) Gram-positive cocci. The most commonly isolated bacteria were Escherichia coli (89 strains) followed by Staphylococcus aureus (48 strains). Thirty-three percent of Gram-negative bacilli were resistant to 3 CG. Forty percent of Klebsiella pneumoniae strains were significantly resistant to imipenem (P = 0.01). CONCLUSIONS: The increased resistance to newly available antibiotics and the increased rate of Gram-positive cocci strains require a drastic surveillance of antibiotic resistance to ensure appropriate empirical treatment.
OBJECTIVES: We wanted to update the distribution of community-acquired uropathogens and to estimate their susceptibility profile to newly available antibiotics in Antananarivo (Madagascar). MATERIALS AND METHODS: We conducted a 3-year preliminary study (2011-2013) on bacteria isolated from the urine of patients at the Laboratory of Training and Research in Medical Biology (Antananarivo). RESULTS: Three hundred and fifty-seven pathogens were isolated: 234 (65.55%) Gram-negative bacilli and 123 (34.45%) Gram-positive cocci. The most commonly isolated bacteria were Escherichia coli (89 strains) followed by Staphylococcus aureus (48 strains). Thirty-three percent of Gram-negative bacilli were resistant to 3 CG. Forty percent of Klebsiella pneumoniae strains were significantly resistant to imipenem (P = 0.01). CONCLUSIONS: The increased resistance to newly available antibiotics and the increased rate of Gram-positive cocci strains require a drastic surveillance of antibiotic resistance to ensure appropriate empirical treatment.
Authors: Noellie Gay; Olivier Belmonte; Jean-Marc Collard; Mohamed Halifa; Mohammad Iqbal Issack; Saindou Mindjae; Philippe Palmyre; Abdul Aziz Ibrahim; Harena Rasamoelina; Loïc Flachet; Laurent Filleul; Eric Cardinale Journal: Front Public Health Date: 2017-07-06
Authors: T Naas; G Cuzon; A L Robinson; Z Andrianirina; P Imbert; E Ratsima; Z N Ranosiarisoa; P Nordmann; J Raymond Journal: BMC Infect Dis Date: 2016-06-10 Impact factor: 3.090