Literature DB >> 25864836

G-quadruplex ligands exhibit differential G-tetrad selectivity.

D D Le1, M Di Antonio, L K M Chan, S Balasubramanian.   

Abstract

A rapid and simple equilibrium-binding assay mediated by ligand-induced fluorescence quenching of fluorophore-labelled G-quadruplex (G4) structures enabled quantitative interrogation of mutually exclusive ligand binding interactions at opposed G-tetrads. This technique revealed that the ligands TmPyP4, PhenDC3, and PDS have differential chemotype-specific binding preferences for individual G-tetrads of a model genomic G4 structure.

Entities:  

Mesh：

Substances：

Year:  2015        PMID： 25864836     DOI： 10.1039/c5cc02252e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  23 in total

1.  Overlapping but distinct: a new model for G-quadruplex biochemical specificity.

Authors:  Martin Volek; Sofia Kolesnikova; Katerina Svehlova; Pavel Srb; Ráchel Sgallová; Tereza Streckerová; Juan A Redondo; Václav Veverka; Edward A Curtis
Journal:  Nucleic Acids Res       Date:  2021-02-26       Impact factor: 16.971

2.  Whole genome experimental maps of DNA G-quadruplexes in multiple species.

Authors:  Giovanni Marsico; Vicki S Chambers; Aleksandr B Sahakyan; Patrick McCauley; Jonathan M Boutell; Marco Di Antonio; Shankar Balasubramanian
Journal:  Nucleic Acids Res       Date:  2019-05-07       Impact factor: 16.971

3.  Biosensor-Surface Plasmon Resonance: Label-Free Method for Investigation of Small Molecule-Quadruplex Nucleic Acid Interactions.

Authors:  Ananya Paul; Caterina Musetti; Rupesh Nanjunda; W David Wilson
Journal:  Methods Mol Biol       Date:  2019

4.  Conformation-sensitive nucleoside analogues as topology-specific fluorescence turn-on probes for DNA and RNA G-quadruplexes.

Authors:  Arun A Tanpure; Seergazhi G Srivatsan
Journal:  Nucleic Acids Res       Date:  2015-07-21       Impact factor: 16.971

5.  Iso-FRET: an isothermal competition assay to analyze quadruplex formation in vitro.

Authors:  Yu Luo; Daniela Verga; Jean-Louis Mergny
Journal:  Nucleic Acids Res       Date:  2022-09-09       Impact factor: 19.160

6.  Cooperative Heteroligand Interaction with G-Quadruplexes Shows Evidence of Allosteric Binding.

Authors:  Shankar Pandey; Yuanyuan Li; Montwaun D Young; Shankar Mandal; Laichun Lu; Jacob T Shelley; Hanbin Mao
Journal:  Biochemistry       Date:  2020-09-03       Impact factor: 3.162

7.  5' to 3' Unfolding Directionality of DNA Secondary Structures by Replication Protein A: G-QUADRUPLEXES AND DUPLEXES.

Authors:  Layal Safa; Nassima Meriem Gueddouda; Frédéric Thiébaut; Emmanuelle Delagoutte; Irina Petruseva; Olga Lavrik; Oscar Mendoza; Anne Bourdoncle; Patrizia Alberti; Jean-François Riou; Carole Saintomé
Journal:  J Biol Chem       Date:  2016-07-19       Impact factor: 5.157

8.  A Dual-App Nucleoside Probe Provides Structural Insights into the Human Telomeric Overhang in Live Cells.

Authors:  Sudeshna Manna; Debayan Sarkar; Seergazhi G Srivatsan
Journal:  J Am Chem Soc       Date:  2018-09-21       Impact factor: 15.419

9.  Conjunction of potential G-quadruplex and adjacent cis-elements in the 5' UTR of hepatocyte nuclear factor 4-alpha strongly inhibit protein expression.

Authors:  Shangdong Guo; Hong Lu
Journal:  Sci Rep       Date:  2017-12-12       Impact factor: 4.379

10.  Probing Human Telomeric DNA and RNA Topology and Ligand Binding in a Cellular Model by Using Responsive Fluorescent Nucleoside Probes.

Authors:  Sudeshna Manna; Cornelia H Panse; Vyankat A Sontakke; Sarangamath Sangamesh; Seergazhi G Srivatsan
Journal:  Chembiochem       Date:  2017-07-10       Impact factor: 3.164
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.