Chelle L Wheat1, Lisa L Strate2. 1. Division of Gastroenterology, Department of Medicine, University of Washington, Seattle, Washington; School of Public Health, Department of Health Services, University of Washington, Seattle, Washington. 2. Division of Gastroenterology, Department of Medicine, University of Washington, Seattle, Washington; Harborview Medical Center, Seattle, Washington. Electronic address: lstrate@uw.edu.
Abstract
BACKGROUND & AIMS: Most studies of trends in diverticular disease have focused on diverticulitis or on a composite outcome of diverticulitis and bleeding. We aimed to quantify and compare the prevalence of hospitalization for diverticular bleeding and diverticulitis overall and by sex and race. METHODS: We analyzed data from the Nationwide Inpatient Sample from 2000 through 2010. We identified adult patients with a discharge diagnosis of diverticular bleeding or diverticulitis. By using yearly US intercensal data, we calculated age-, sex-, and race-specific rates, as well as age-adjusted prevalence rates. RESULTS: The prevalence of hospitalizations per 100,000 persons for diverticular bleeding decreased over the 10-year period from 32.5 to 27.1 (-5.4; 95% confidence interval, -5.1 to -5.7). The prevalence of hospitalizations for diverticulitis peaked in 2008 (74.1/100,000 in 2000, 96.0/100,000 in 2008, and 91.9/100,000 in 2010). The prevalence of diverticulitis was higher in women than in men, whereas women and men had similar rates of diverticular bleeding. The prevalence of diverticular bleeding was highest in blacks (34.4/100,000 in 2010); whereas the prevalence of diverticulitis was highest in whites (75.5/100,000 in 2010). CONCLUSIONS: Over the past 10 years, the prevalence of hospitalizations for diverticulitis increased and then plateaued, whereas that of diverticular bleeding decreased. The prevalence according to sex and race differed for diverticulitis and diverticular bleeding. These findings indicate different mechanisms of pathogenesis for these disorders.
BACKGROUND & AIMS: Most studies of trends in diverticular disease have focused on diverticulitis or on a composite outcome of diverticulitis and bleeding. We aimed to quantify and compare the prevalence of hospitalization for diverticular bleeding and diverticulitis overall and by sex and race. METHODS: We analyzed data from the Nationwide Inpatient Sample from 2000 through 2010. We identified adult patients with a discharge diagnosis of diverticular bleeding or diverticulitis. By using yearly US intercensal data, we calculated age-, sex-, and race-specific rates, as well as age-adjusted prevalence rates. RESULTS: The prevalence of hospitalizations per 100,000 persons for diverticular bleeding decreased over the 10-year period from 32.5 to 27.1 (-5.4; 95% confidence interval, -5.1 to -5.7). The prevalence of hospitalizations for diverticulitis peaked in 2008 (74.1/100,000 in 2000, 96.0/100,000 in 2008, and 91.9/100,000 in 2010). The prevalence of diverticulitis was higher in women than in men, whereas women and men had similar rates of diverticular bleeding. The prevalence of diverticular bleeding was highest in blacks (34.4/100,000 in 2010); whereas the prevalence of diverticulitis was highest in whites (75.5/100,000 in 2010). CONCLUSIONS: Over the past 10 years, the prevalence of hospitalizations for diverticulitis increased and then plateaued, whereas that of diverticular bleeding decreased. The prevalence according to sex and race differed for diverticulitis and diverticular bleeding. These findings indicate different mechanisms of pathogenesis for these disorders.
Authors: Anne F Peery; Patrick R Barrett; Doyun Park; Albert J Rogers; Joseph A Galanko; Christopher F Martin; Robert S Sandler Journal: Gastroenterology Date: 2011-11-04 Impact factor: 22.682
Authors: Keith C Ferdinand; Fatima Rodriguez; Samar A Nasser; A Enrique Caballero; Gary A Puckrein; Farhad Zangeneh; Michael Mansour; JoAnne Micale Foody; Priscilla E Pemu; Elizabeth O Ofili Journal: Cardiorenal Med Date: 2013-12-31 Impact factor: 2.041
Authors: Lisa L Strate; Yan L Liu; Edward S Huang; Edward L Giovannucci; Andrew T Chan Journal: Gastroenterology Date: 2011-02-12 Impact factor: 22.682
Authors: Angel Lanas; Luis A García-Rodríguez; Mónica Polo-Tomás; Marta Ponce; Inmaculada Alonso-Abreu; Maria Angeles Perez-Aisa; Javier Perez-Gisbert; Luis Bujanda; Manuel Castro; Maria Muñoz; Luis Rodrigo; Xavier Calvet; Dolores Del-Pino; Santiago Garcia Journal: Am J Gastroenterol Date: 2009-05-05 Impact factor: 10.864
Authors: J Y Kang; J Hoare; A Tinto; S Subramanian; C Ellis; A Majeed; D Melville; J D Maxwell Journal: Aliment Pharmacol Ther Date: 2003-05-01 Impact factor: 8.171
Authors: Bob Marshall; Shailendra Prasad; Mary A Noel; Jeffrey Burket; Michael Arnold; Benjamin Arthur; Nick Bennett; Ashley Smith Journal: J Fam Pract Date: 2018-07 Impact factor: 0.493
Authors: Gian Andrea Binda; F Mataloni; M Bruzzone; M Carabotti; R Cirocchi; R Nascimbeni; G Gambassi; A Amato; N Vettoretto; L Pinnarelli; R Cuomo; B Annibale Journal: Tech Coloproctol Date: 2018-09-08 Impact factor: 3.781
Authors: Lisa L Strate; Brieze R Keeley; Yin Cao; Kana Wu; Edward L Giovannucci; Andrew T Chan Journal: Gastroenterology Date: 2017-01-05 Impact factor: 22.682
Authors: Manol Jovani; Wenjie Ma; Amit D Joshi; Po-Hong Liu; Long H Nguyen; Yin Cao; Idy Tam; Kana Wu; Edward L Giovannucci; Andrew T Chan; Lisa L Strate Journal: Am J Gastroenterol Date: 2019-02 Impact factor: 10.864
Authors: Po-Hong Liu; Yin Cao; Brieze R Keeley; Idy Tam; Kana Wu; Lisa L Strate; Edward L Giovannucci; Andrew T Chan Journal: Am J Gastroenterol Date: 2017-11-07 Impact factor: 10.864
Authors: A Amato; F Mataloni; M Bruzzone; M Carabotti; R Cirocchi; R Nascimbeni; G Gambassi; N P Vettoretto; L Pinnarelli; R Cuomo; B Annibale; V Fontana; G A Binda Journal: Tech Coloproctol Date: 2020-02-04 Impact factor: 3.781