Literature DB >> 25862552

Can genomic medicine improve financial sustainability of health systems?

Christine Y Lu1, Joshua P Cohen.   

Abstract

Recent years have seen increased use of genomic technologies in a variety of research and clinical settings. Genomic medicine is not a cost-containment measure per se, but is viewed as having the potential to bend the healthcare cost curve. Currently, it is unknown how systematic adoption of genomic medicine in clinical practice will impact healthcare costs. This article discusses the potential economic impact of genomic medicine and the challenges that lie ahead.

Mesh:

Year:  2015        PMID: 25862552     DOI: 10.1007/s40291-015-0138-3

Source DB:  PubMed          Journal:  Mol Diagn Ther        ISSN: 1177-1062            Impact factor:   4.074


  25 in total

1.  A vision for the future of genomics research.

Authors:  Francis S Collins; Eric D Green; Alan E Guttmacher; Mark S Guyer
Journal:  Nature       Date:  2003-04-14       Impact factor: 49.962

2.  New Automated HER2 Test Promises Faster, More Accurate Testing.

Authors:  Bob Carlson
Journal:  Biotechnol Healthc       Date:  2011

Review 3.  Overcoming regulatory and economic challenges facing pharmacogenomics.

Authors:  Joshua P Cohen
Journal:  N Biotechnol       Date:  2012-02-19       Impact factor: 5.079

4.  Health care reform and cost control.

Authors:  Peter R Orszag; Ezekiel J Emanuel
Journal:  N Engl J Med       Date:  2010-06-16       Impact factor: 91.245

Review 5.  High and rising health care costs. Part 2: technologic innovation.

Authors:  Thomas Bodenheimer
Journal:  Ann Intern Med       Date:  2005-06-07       Impact factor: 25.391

6.  The economics of genomic medicine: insights from the IOM Roundtable on Translating Genomic-Based Research for Health.

Authors:  W Gregory Feero; Catherine Wicklund; David L Veenstra
Journal:  JAMA       Date:  2013-03-27       Impact factor: 56.272

7.  Implementation of genomic medicine in a health care delivery system: a value proposition?

Authors:  Joanne E Wade; David H Ledbetter; Marc S Williams
Journal:  Am J Med Genet C Semin Med Genet       Date:  2014-03-11       Impact factor: 3.908

8.  Clinical whole-exome sequencing: are we there yet?

Authors:  Paldeep Singh Atwal; Marie-Louise Brennan; Rachel Cox; Michael Niaki; Julia Platt; Margaret Homeyer; Andrea Kwan; Sylvie Parkin; Susan Schelley; Leah Slattery; Yael Wilnai; Jonathan Adam Bernstein; Gregory M Enns; Louanne Hudgins
Journal:  Genet Med       Date:  2014-02-13       Impact factor: 8.822

9.  Personalized Medicine's Bottleneck: Diagnostic Test Evidence and Reimbursement.

Authors:  Joshua P Cohen; Abigail E Felix
Journal:  J Pers Med       Date:  2014-04-04

Review 10.  Understanding the economic value of molecular diagnostic tests: case studies and lessons learned.

Authors:  Adrian Towse; Diego Ossa; David Veenstra; Josh Carlson; Louis Garrison
Journal:  J Pers Med       Date:  2013-10-25
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  6 in total

1.  Estimating Preferences for Complex Health Technologies: Lessons Learned and Implications for Personalized Medicine.

Authors:  Deborah A Marshall; Juan Marcos Gonzalez; Karen V MacDonald; F Reed Johnson
Journal:  Value Health       Date:  2017-01       Impact factor: 5.725

2.  Clinical Molecular Marker Testing Data Capture to Promote Precision Medicine Research Within the Cancer Research Network.

Authors:  Andrea N Burnett-Hartman; Natalia Udaltsova; Lawrence H Kushi; Christine Neslund-Dudas; Alanna Kulchak Rahm; Pamala A Pawloski; Douglas A Corley; Sarah Knerr; Heather Spencer Feigelson; Jessica Ezzell Hunter; David C Tabano; Mara M Epstein; Stacey A Honda; Monica Ter-Minassian; Julie A Lynch; Christine Y Lu
Journal:  JCO Clin Cancer Inform       Date:  2019-09

Review 3.  A proposed approach to accelerate evidence generation for genomic-based technologies in the context of a learning health system.

Authors:  Christine Y Lu; Marc S Williams; Geoffrey S Ginsburg; Sengwee Toh; Jeff S Brown; Muin J Khoury
Journal:  Genet Med       Date:  2017-08-10       Impact factor: 8.822

Review 4.  Conceptualising 'Benefits Beyond Health' in the Context of the Quality-Adjusted Life-Year: A Critical Interpretive Synthesis.

Authors:  Lidia Engel; Stirling Bryan; David G T Whitehurst
Journal:  Pharmacoeconomics       Date:  2021-08-23       Impact factor: 4.981

5.  Longitudinal trends in use of targeted therapies for treatment of malignant neoplasms of the eye: a population-based study in Taiwan.

Authors:  Jason C Hsu; Luis A Gonzalez-Gonzalez; Vicky H Lu; Christine Y Lu
Journal:  BMJ Open       Date:  2016-05-27       Impact factor: 2.692

6.  Longitudinal trends in use and costs of targeted therapies for common cancers in Taiwan: a retrospective observational study.

Authors:  Jason C Hsu; Christine Y Lu
Journal:  BMJ Open       Date:  2016-06-06       Impact factor: 2.692

  6 in total

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