Literature DB >> 25859439

A glimpse towards the vestigiality and fate of human vermiform appendix-a histomorphometric study.

Aniruddha Sarkar1, Anubha Saha2, Sanchita Roy2, Santanu Pathak3, Shyamash Mandal3.   

Abstract

INTRODUCTION: The vermiform appendix in human is considered to be a vestigial organ by most of the authors. Absence of appendix is already reported in Indian population. Whether the human appendix is performing any function is debatable but when present it can create trouble. So if there is no appendix we can escape the ill-effects of the organ. With this hope the study has been done to see whether the appendix is really going to be rudimentary or absent or not. Marerials and
Methods: Length, external diameter, number of lymphoid follicles, maximum diameter of the follicle or submucous coat, thickening of the muscle coat and seromucosal thickening of freshly removed appendix from human cadavers were seen. After fixation in 10% formal saline tissues were stained with haematoxylin-eosin stain and photographs were taken. The results had been tabulated and statistically correlated. RESULT: The parameters like number of lymphoid follicles, length and diameter all are changed as per the age advancement which is strictly indicating some functional activities of the organ which is against the idea of vestigiality of the appendix.
CONCLUSION: Human appendix cannot be called a vestigial organ unless the functional inactivity is proved. Lymphoid changes which occur after birth to provide the gut immunity is needed to be proved by further studies. There might be incidental absence or rudimentary appendix in human body, but that does not indicate that we would not have any appendix in future.

Entities:  

Keywords:  Agenesis; Appendicitis; Vestigial organ

Year:  2015        PMID: 25859439      PMCID: PMC4378721          DOI: 10.7860/JCDR/2015/11178.5581

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  14 in total

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Authors:  Noh Hyuck Park; Hwa Eun Oh; Hee Jin Park; Ji Yeon Park
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  3 in total

1.  Papio spp. Colon microbiome and its link to obesity in pregnancy.

Authors:  XuanJi Li; Christopher Rensing; William L Taylor; Caitlin Costelle; Asker Daniel Brejnrod; Robert J Ferry; Paul B Higgins; Franco Folli; Kameswara Rao Kottapalli; Gene B Hubbard; Edward J Dick; Shibu Yooseph; Karen E Nelson; Natalia Schlabritz-Loutsevitch
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2.  Appendectomy as a Risk Factor for Bacteremic Biliary Tract Infection Caused by Antibiotic-Resistant Pathogens.

Authors:  Koki Kawanishi; Jun Kinoshita; Hiroko Abe; Tetsuhiro Kakimoto; Yuko Yasuda; Takeshi Hara; Jun Kato
Journal:  Biomed Res Int       Date:  2017-05-15       Impact factor: 3.411

3.  Incidence and risk of sepsis following appendectomy: a nationwide population-based cohort study.

Authors:  Meng-Che Wu; Hsi-Kai Tsou; Cheng-Li Lin; James Cheng-Chung Wei
Journal:  Sci Rep       Date:  2020-06-23       Impact factor: 4.379

  3 in total

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