Literature DB >> 2585102

A model of the peritoneal cavity for use in internal dosimetry.

E E Watson1, M G Stabin, J L Davis, K F Eckerman.   

Abstract

Several therapeutic and diagnostic techniques involve injection of radioactive material into the peritoneal cavity. Estimation of the radiation dose to the surface of the peritoneum or to surrounding organs is hampered by the lack of a suitable source region in the phantom commonly used for such calculations. We have modified the Fisher-Snyder phantom to include a region representing the peritoneal cavity which may be employed to estimate such radiation doses. A geometric model is described which is coordinated with the existing organ regions in the phantom. Specific absorbed fractions (derived by Monte Carlo techniques) for photon emissions originating within the cavity are listed. Photon S-values for several radionuclides which have been administered intraperitoneally are shown. Dose conversion factors for electrons irradiating the peritoneal cavity wall, from either a thin plane or volume source of activity within the cavity, are also given for several nuclides.

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Year:  1989        PMID: 2585102

Source DB:  PubMed          Journal:  J Nucl Med        ISSN: 0161-5505            Impact factor:   10.057


  4 in total

1.  Two-step tumour targetting in ovarian cancer patients using biotinylated monoclonal antibodies and radioactive streptavidin.

Authors:  G Paganelli; C Belloni; P Magnani; F Zito; A Pasini; I Sassi; M Meroni; M Mariani; M Vignali; A G Siccardi
Journal:  Eur J Nucl Med       Date:  1992

2.  Biodistribution and Radiation Dosimetry of Intraperitoneally Administered 124I-Omburtamab in Patients with Desmoplastic Small Round Cell Tumors.

Authors:  Milan Grkovski; Shakeel Modak; Pat B Zanzonico; Jorge A Carrasquillo; Steven M Larson; John L Humm; Neeta Pandit-Taskar
Journal:  J Nucl Med       Date:  2021-12-02       Impact factor: 11.082

Review 3.  Radiopharmaceutical therapy in cancer: clinical advances and challenges.

Authors:  George Sgouros; Lisa Bodei; Michael R McDevitt; Jessie R Nedrow
Journal:  Nat Rev Drug Discov       Date:  2020-07-29       Impact factor: 84.694

4.  B7H3-Directed Intraperitoneal Radioimmunotherapy With Radioiodinated Omburtamab for Desmoplastic Small Round Cell Tumor and Other Peritoneal Tumors: Results of a Phase I Study.

Authors:  Shakeel Modak; Pat Zanzonico; Milan Grkovski; Emily K Slotkin; Jorge A Carrasquillo; Serge K Lyashchenko; Jason S Lewis; Irene Y Cheung; Todd Heaton; Michael P LaQuaglia; Nai-Kong V Cheung; Neeta Pandit-Taskar
Journal:  J Clin Oncol       Date:  2020-10-29       Impact factor: 44.544

  4 in total

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