Literature DB >> 25850616

Multi-layered polymeric nanoparticles for pH-responsive and sequenced release of theranostic agents.

Hai Wang1, Shuting Zhao, Pranay Agarwal, Jenna Dumbleton, Jianhua Yu, Xiongbin Lu, Xiaoming He.   

Abstract

In this study, multi-layered pH-responsive polymeric nanoparticles (NPs) are prepared by multiple (up to 4) emulsifications to encapsulate multiple hydrophilic and hydrophobic theranostic agents for controlled and sequenced release. It is found that the sequence of release of multiple chemotherapeutic agents from the NPs significantly affects their efficacy against cancer cells.

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Year:  2015        PMID： 25850616     DOI： 10.1039/c5cc01833a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

1.  Nanoparticles for Targeted Drug Delivery to Cancer Stem Cells and Tumor.

Authors:  Hai Wang; Xiaoming He
Journal:  Methods Mol Biol       Date:  2018

2.  Self-carried curcumin nanoparticles for in vitro and in vivo cancer therapy with real-time monitoring of drug release.

Authors:  Jinfeng Zhang; Shengliang Li; Fei-Fei An; Juan Liu; Shubin Jin; Jin-Chao Zhang; Paul C Wang; Xiaohong Zhang; Chun-Sing Lee; Xing-Jie Liang
Journal:  Nanoscale       Date:  2015-07-22       Impact factor: 7.790

3.  NANOPARTICLE-MEDIATED DELIVERY OF CRYOPROTECTANTS FOR CRYOPRESERVATION.

Authors:  Samantha Stewart; Alyssa Arminan; Xiaoming He
Journal:  Cryo Letters       Date:  2020 Nov-Dec       Impact factor: 0.892

4.  A biomimetic hybrid nanoplatform for encapsulation and precisely controlled delivery of theranostic agents. [Corrected].

Authors:  Hai Wang; Pranay Agarwal; Shuting Zhao; Jianhua Yu; Xiongbin Lu; Xiaoming He
Journal:  Nat Commun       Date:  2015-12-01       Impact factor: 14.919

5.  Precise targeting of POLR2A as a therapeutic strategy for human triple negative breast cancer.

Authors:  Jiangsheng Xu; Yunhua Liu; Yujing Li; Hai Wang; Samantha Stewart; Kevin Van der Jeught; Pranay Agarwal; Yuntian Zhang; Sheng Liu; Gang Zhao; Jun Wan; Xiongbin Lu; Xiaoming He
Journal:  Nat Nanotechnol       Date:  2019-02-25       Impact factor: 39.213

6.  A Nano-In-Micro System for Enhanced Stem Cell Therapy of Ischemic Diseases.

Authors:  Hai Wang; Pranay Agarwal; Yichao Xiao; Hao Peng; Shuting Zhao; Xuanyou Liu; Shenghua Zhou; Jianrong Li; Zhenguo Liu; Xiaoming He
Journal:  ACS Cent Sci       Date:  2017-07-19       Impact factor: 14.553
  6 in total

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