Lars Vedel Kessing1, Eleni Vradi2, Per Kragh Andersen2. 1. Psychiatric Center Copenhagen, Department O, University of Copenhagen, Copenhagen, Denmark. 2. Department of Biostatistics, University of Copenhagen, Copenhagen, Denmark.
Abstract
OBJECTIVE: Life expectancy in patients with bipolar disorder has been reported to be decreased by 11 to 20 years. These calculations are based on data for individuals at the age of 15 years. However, this may be misleading for patients with bipolar disorder in general as most patients have a later onset of illness. The aim of the present study was to calculate the remaining life expectancy for patients of different ages with a diagnosis of bipolar disorder. METHODS: Using nationwide registers of all inpatient and outpatient contacts to all psychiatric hospitals in Denmark from 1970 to 2012 we calculated remaining life expectancies for values of age 15, 25, 35 ⃛ 75 years among all individuals alive in year 2000. RESULTS: For the typical male or female patient aged 25 to 45 years, the remaining life expectancy was decreased by 12.0-8.7 years and 10.6-8.3 years, respectively. The ratio between remaining life expectancy in bipolar disorder and that of the general population decreased with age, indicating that patients with bipolar disorder start losing life-years during early and mid-adulthood. CONCLUSIONS: Life expectancy in bipolar disorder is decreased substantially, but less so than previously reported. Patients start losing life-years during early and mid-adulthood.
OBJECTIVE: Life expectancy in patients with bipolar disorder has been reported to be decreased by 11 to 20 years. These calculations are based on data for individuals at the age of 15 years. However, this may be misleading for patients with bipolar disorder in general as most patients have a later onset of illness. The aim of the present study was to calculate the remaining life expectancy for patients of different ages with a diagnosis of bipolar disorder. METHODS: Using nationwide registers of all inpatient and outpatient contacts to all psychiatric hospitals in Denmark from 1970 to 2012 we calculated remaining life expectancies for values of age 15, 25, 35 ⃛ 75 years among all individuals alive in year 2000. RESULTS: For the typical male or female patient aged 25 to 45 years, the remaining life expectancy was decreased by 12.0-8.7 years and 10.6-8.3 years, respectively. The ratio between remaining life expectancy in bipolar disorder and that of the general population decreased with age, indicating that patients with bipolar disorder start losing life-years during early and mid-adulthood. CONCLUSIONS: Life expectancy in bipolar disorder is decreased substantially, but less so than previously reported. Patients start losing life-years during early and mid-adulthood.
Authors: Martin Strassnig; Roman Kotov; Danielle Cornaccio; Laura Fochtmann; Philip D Harvey; Evelyn J Bromet Journal: Bipolar Disord Date: 2017-06-02 Impact factor: 6.744
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Authors: Lumbini Azim; Paul Hindmarch; Georgiana Browne; Thomas Chadwick; Emily Clare; Paul Courtney; Lyndsey Dixon; Nichola Duffelen; Tony Fouweather; John R Geddes; Nicola Goudie; Sandy Harvey; Timea Helter; Eva-Maria Holstein; Garry Martin; Phil Mawson; Jenny McCaffery; Richard Morriss; Judit Simon; Daniel Smith; Paul R A Stokes; Jenn Walker; Chris Weetman; Faye Wolstenhulme; Allan H Young; Stuart Watson; R Hamish McAllister-Williams Journal: BMC Psychiatry Date: 2021-07-05 Impact factor: 3.630