| Literature DB >> 25845881 |
Rita Caramalho1, Elisabeth Maurer1, Ulrike Binder1, Ricardo Araújo2, Somayeh Dolatabadi3, Cornelia Lass-Flörl1, Michaela Lackner4.
Abstract
Amphotericin B and posaconazole susceptibility patterns were determined for the most prevalent Mucorales, following EUCAST (European Committee on Antimicrobial Susceptibility Testing) broth microdilution guidelines. In parallel, Etest was performed and evaluated against EUCAST. The overall agreement of MICs gained with Etest and EUCAST was 75.1%; therefore, Etest cannot be recommended for antifungal susceptibility testing of Mucorales. Amphotericin B was the most active drug against Mucorales species in vitro, while the activities of posaconazole were more restricted.Entities:
Mesh:
Substances:
Year: 2015 PMID: 25845881 PMCID: PMC4432123 DOI: 10.1128/AAC.00004-15
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191