| Literature DB >> 25451049 |
Elisabeth Maurer1, Ulrike Binder2, Manuela Sparber1, Michaela Lackner1, Rita Caramalho1, Cornelia Lass-Flörl1.
Abstract
The effect of hypoxic conditions on the in vitro efficacy of amphotericin B and posaconazole against Mucorales was evaluated by defining MICs with Etest and broth microdilution and identifying minimal fungicidal concentrations (MFCs). With Etest, oxygen-dependent changes were detected, while the MIC and the MFC determined with broth microdilution remained unaltered with reduced oxygen levels. The observed differences depended on the method used.Entities:
Mesh:
Substances:
Year: 2014 PMID: 25451049 PMCID: PMC4335829 DOI: 10.1128/AAC.04424-14
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191