| Literature DB >> 25841656 |
Xhevat Lumi1, Marko Hawlina2, Damjan Glavač3, Andrea Facskó4, Morten C Moe5, Kai Kaarniranta6, Goran Petrovski7.
Abstract
Floaters and flashes are most commonly symptoms of age-related degenerative changes in the vitreous body and posterior vitreous detachment. The etiology and pathogenesis of floaters' formation is still not well understood. Patients with acute-onset floaters, flashes and defects in their visual field, represent a medical emergency with the need for same day referral to an ophthalmologist. Indirect ophthalmoscopy with scleral indentation is needed in order to find possible retinal break(s), on-time treatment and prevention of retinal detachment. The molecular and genetic pathogenesis, as well as the epidemiology of the ageing changes of the vitreous is summarized here, with view on the several treatment modalities in relation to their success rate and side-effects.Entities:
Keywords: Acute-onset floaters; Ageing of the vitreous; Flashes; Photopsia; Posterior vitreous detachment; Retinal detachment
Mesh：
Year: 2015 PMID： 25841656 DOI： 10.1016/j.arr.2015.03.006
Source DB: PubMed Journal: Ageing Res Rev ISSN： 1568-1637 Impact factor: 10.895