PURPOSE: The aim of this study was to provide some useful insights into the clinical and imaging presentations, treatment and prognostic factors in patients with neurological deficit caused by clear cell renal cell carcinoma (CCRCC) spinal metastases for the sake of designing individualized therapeutic plans for such patients. METHODS: A total of 30 patients with neurological deficit due to CCRCC spinal metastases who received surgery in our department were identified during an 8-year period from 2003 to 2012 and used for discussion of treatment options for CCRCC spinal metastases on the basis of literature review and our own experience. RESULTS: Univariate analysis showed that age (≤45 years/>45 years), visceral metastasis, Tomita score (3-5/6-8), Tokuhashi score (4-9/10-12) and radiotherapy were suggested as the potential prognostic factors. However, the multivariate Cox regression model showed that only Tokuhashi score was an independent prognostic factor. CONCLUSIONS: Tokuhashi score 10 or more is a favorable prognostic factor of CCRCC spinal metastasis.
PURPOSE: The aim of this study was to provide some useful insights into the clinical and imaging presentations, treatment and prognostic factors in patients with neurological deficit caused by clear cell renal cell carcinoma (CCRCC) spinal metastases for the sake of designing individualized therapeutic plans for such patients. METHODS: A total of 30 patients with neurological deficit due to CCRCC spinal metastases who received surgery in our department were identified during an 8-year period from 2003 to 2012 and used for discussion of treatment options for CCRCC spinal metastases on the basis of literature review and our own experience. RESULTS: Univariate analysis showed that age (≤45 years/>45 years), visceral metastasis, Tomita score (3-5/6-8), Tokuhashi score (4-9/10-12) and radiotherapy were suggested as the potential prognostic factors. However, the multivariate Cox regression model showed that only Tokuhashi score was an independent prognostic factor. CONCLUSIONS: Tokuhashi score 10 or more is a favorable prognostic factor of CCRCC spinal metastasis.
Authors: Yoshiya Yamada; Mark H Bilsky; D Michael Lovelock; Ennapadam S Venkatraman; Sean Toner; Jared Johnson; Joan Zatcky; Michael J Zelefsky; Zvi Fuks Journal: Int J Radiat Oncol Biol Phys Date: 2008-01-30 Impact factor: 7.038
Authors: Benjamin Ulmar; Marcus Richter; Balkan Cakir; Rainer Muche; Wolfhart Puhl; Klaus Huch Journal: Spine (Phila Pa 1976) Date: 2005-10-01 Impact factor: 3.468
Authors: N Robial; Y-P Charles; I Bogorin; J Godet; R Beaujeux; F Boujan; J-P Steib Journal: Orthop Traumatol Surg Res Date: 2012-07-17 Impact factor: 2.256
Authors: C Rory Goodwin; A Karim Ahmed; Christine Boone; Nancy Abu-Bonsrah; Risheng Xu; Niccole Germscheid; Daryl R Fourney; Michelle Clarke; Ilya Laufer; Charles G Fisher; Chetan Bettegowda; Daniel M Sciubba Journal: Global Spine J Date: 2017-11-20