Literature DB >> 25839428

Cylindrical diffuser axial detection profile is dependent on fiber design.

Timothy M Baran.   

Abstract

The axial emission and detection profiles of 1- and 2-cm cylindrical diffusing fibers based on concentration gradients of scatterers were measured. Based on these measurements, we describe a method for determination of the scatterer concentration gradient within the diffusers. Using a Monte Carlo model incorporating these concentrations, detection was simulated and found to agree with measurements. The measured and simulated detection profiles for these diffusers were found to be drastically different from those previously measured in an alternative diffuser design incorporating an end reflector. When using cylindrical diffusers as detection fibers, it is, therefore, important to understand the design of the fiber and characterize the detection behavior.

Mesh:

Year:  2015        PMID: 25839428      PMCID: PMC4383839          DOI: 10.1117/1.JBO.20.4.040502

Source DB:  PubMed          Journal:  J Biomed Opt        ISSN: 1083-3668            Impact factor:   3.170


  10 in total

1.  Performance evaluation of cylindrical fiber optic light diffusers for biomedical applications.

Authors:  Leonid M Vesselov; William Whittington; Lothar Lilge
Journal:  Lasers Surg Med       Date:  2004       Impact factor: 4.025

Review 2.  The physics, biophysics and technology of photodynamic therapy.

Authors:  Brian C Wilson; Michael S Patterson
Journal:  Phys Med Biol       Date:  2008-04-09       Impact factor: 3.609

3.  Determination of optical properties by interstitial white light spectroscopy using a custom fiber optic probe.

Authors:  Timothy M Baran; Michael C Fenn; Thomas H Foster
Journal:  J Biomed Opt       Date:  2013-10       Impact factor: 3.170

4.  Light distribution by linear diffusing sources for photodynamic therapy.

Authors:  L H Murrer; J P Marijnissen; W M Star
Journal:  Phys Med Biol       Date:  1996-06       Impact factor: 3.609

5.  New Monte Carlo model of cylindrical diffusing fibers illustrates axially heterogeneous fluorescence detection: simulation and experimental validation.

Authors:  Timothy M Baran; Thomas H Foster
Journal:  J Biomed Opt       Date:  2011-08       Impact factor: 3.170

Review 6.  Photodynamic therapy of cancer: an update.

Authors:  Patrizia Agostinis; Kristian Berg; Keith A Cengel; Thomas H Foster; Albert W Girotti; Sandra O Gollnick; Stephen M Hahn; Michael R Hamblin; Asta Juzeniene; David Kessel; Mladen Korbelik; Johan Moan; Pawel Mroz; Dominika Nowis; Jacques Piette; Brian C Wilson; Jakub Golab
Journal:  CA Cancer J Clin       Date:  2011-05-26       Impact factor: 508.702

7.  Determination of the distribution of light, optical properties, drug concentration, and tissue oxygenation in-vivo in human prostate during motexafin lutetium-mediated photodynamic therapy.

Authors:  Timothy C Zhu; Jarod C Finlay; Stephen M Hahn
Journal:  J Photochem Photobiol B       Date:  2004-12-02       Impact factor: 6.252

8.  Motexafin lutetium-photodynamic therapy of prostate cancer: short- and long-term effects on prostate-specific antigen.

Authors:  Hiral Patel; Rosemarie Mick; Jarod Finlay; Timothy C Zhu; Elizabeth Rickter; Keith A Cengel; S Bruce Malkowicz; Stephen M Hahn; Theresa M Busch
Journal:  Clin Cancer Res       Date:  2008-08-01       Impact factor: 12.531

9.  Determination of optical properties in heterogeneous turbid media using a cylindrical diffusing fiber.

Authors:  Andreea Dimofte; Jarod C Finlay; Xing Liang; Timothy C Zhu
Journal:  Phys Med Biol       Date:  2012-09-12       Impact factor: 3.609

10.  Recovery of intrinsic fluorescence from single-point interstitial measurements for quantification of doxorubicin concentration.

Authors:  Timothy M Baran; Thomas H Foster
Journal:  Lasers Surg Med       Date:  2013-08-23       Impact factor: 4.025

  10 in total
  1 in total

1.  Recovery of optical properties using interstitial cylindrical diffusers as source and detector fibers.

Authors:  Timothy M Baran
Journal:  J Biomed Opt       Date:  2016-07-01       Impact factor: 3.170

  1 in total

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