Takako Miki1, Takeshi Kochi2, Masafumi Eguchi2, Keisuke Kuwahara3, Hiroko Tsuruoka2, Kayo Kurotani4, Rie Ito2, Shamima Akter4, Ikuko Kashino4, Ngoc Minh Pham5, Isamu Kabe2, Norito Kawakami6, Tetsuya Mizoue4, Akiko Nanri4. 1. Department of Epidemiology and Prevention, Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan; Department of Mental Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. Electronic address: Takakomiki-tky@umin.ac.jp. 2. Department of Health Administration, Furukawa Electric Corporation, Tokyo, Japan. 3. Department of Epidemiology and Prevention, Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan; Teikyo University Graduate School of Public Health, Tokyo, Japan. 4. Department of Epidemiology and Prevention, Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan. 5. Department of Epidemiology, Faculty of Public Health, Thai Nguyen University of Medicine and Pharmacy, Thai Nguyen Province, Vietnam. 6. Department of Mental Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Abstract
OBJECTIVE: Although intake of minerals has been suggested to be beneficial against depression, epidemiologic data from free-living settings are limited. The aim of this study was to determine the cross-sectional associations between the intake of magnesium, calcium, iron, and zinc and the prevalence of depressive symptoms in Japanese employees. METHODS: Participants were 1792 men and 214 women ages 19 to 69 y. Dietary intake was assessed using a validated, brief self-administered diet history questionnaire. Participants with depressive symptoms were defined as those with a scale score of ≥16 on the Center for Epidemiologic Studies Depression Scale. RESULTS: The prevalence of depressive symptoms was 27.8%. Intakes of magnesium, calcium, iron, and zinc were inversely associated with the prevalence of depressive symptoms. The multivariate adjusted odds ratios (95% confidence interval) of having depressive symptoms were 0.63 (0.44-0.91), 0.64 (0.47-0.88), 0.59 (0.40-0.87), and 0.63 (0.45-0.87) in the highest versus lowest tertiles of magnesium, calcium, iron, and zinc, respectively. CONCLUSION: Results suggest that higher dietary intake of magnesium, calcium, iron, and zinc is associated with lower prevalence of depressive symptoms in Japanese employees.
OBJECTIVE: Although intake of minerals has been suggested to be beneficial against depression, epidemiologic data from free-living settings are limited. The aim of this study was to determine the cross-sectional associations between the intake of magnesium, calcium, iron, and zinc and the prevalence of depressive symptoms in Japanese employees. METHODS:Participants were 1792 men and 214 women ages 19 to 69 y. Dietary intake was assessed using a validated, brief self-administered diet history questionnaire. Participants with depressive symptoms were defined as those with a scale score of ≥16 on the Center for Epidemiologic Studies Depression Scale. RESULTS: The prevalence of depressive symptoms was 27.8%. Intakes of magnesium, calcium, iron, and zinc were inversely associated with the prevalence of depressive symptoms. The multivariate adjusted odds ratios (95% confidence interval) of having depressive symptoms were 0.63 (0.44-0.91), 0.64 (0.47-0.88), 0.59 (0.40-0.87), and 0.63 (0.45-0.87) in the highest versus lowest tertiles of magnesium, calcium, iron, and zinc, respectively. CONCLUSION: Results suggest that higher dietary intake of magnesium, calcium, iron, and zinc is associated with lower prevalence of depressive symptoms in Japanese employees.
Authors: Y Yokoyama; A Kitamura; T Yoshizaki; M Nishi; S Seino; Y Taniguchi; H Amano; M Narita; S Shinkai Journal: J Nutr Health Aging Date: 2019 Impact factor: 4.075
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Authors: Nuria Rubio-López; María Morales-Suárez-Varela; Yolanda Pico; Lorenzo Livianos-Aldana; Agustín Llopis-González Journal: Int J Environ Res Public Health Date: 2016-03-22 Impact factor: 3.390