Literature DB >> 25835113

Epidemiology of colorectal cancer in Turkey: A cross-sectional disease registry study (A Turkish Oncology Group trial).

Nuri Faruk Aykan1, Suayib Yalçın, N Serdar Turhal, Mustafa Özdoğan, Gökhan Demir, Metin Özkan, Arzu Yaren, Celalettin Camcı, Hakan Akbulut, Mehmet Artaç, Nezih Meydan, Kazim Uygun, Abdurrahman Işıkdoğan, Diclehan Ünsal, Özgür Özyılkan, Ali Arıcan, Ertuğrul Seyrek, Salim Başol Tekin, Osman Manavoğlu, Ahmet Özet, Tamer Elkıran, Rian Dişçi.   

Abstract

BACKGROUND/AIMS: This study aimed to determine the epidemiological characteristics of colorectal cancer in Turkey.
MATERIALS AND METHODS: In this multicenter, prospective, and cross-sectional registry study, data for 968 patients with colorectal cancer from 21 centers in 7 geographic regions were analyzed.
RESULTS: Diagnosis was colon cancer in 662 (68.4%) and rectum cancer in 306 (31.6%) patients. In total, 60.9% of patients was male; mean age was 58.9±12.6 years. Among patients, 15.0% was drinking alcohol, 17.5% was smoking, 1.5% had familial history of polyposis, 15.0% had diabetes mellitus, 1.0% had inflammatory bowel disease. Fruit and vegetable consumption was low (<3 times/week) in 35.5% and red meat consumption was high (≥3 times/week) in 47.4% of the patients. Median time-to diagnosis was 3.0 months and 4.0 months for patients with colon and rectum cancer, respectively. Mean body mass index was >25 in all group of patients. Distal rectum (61.3%) and sigmoid colon (36.8%) were the most common locations of cancer, for rectum and colon respectively. In total, 85.6% of patients were operated; 25.8% had emergency surgery. Low anterior resection rate was 64.2% in rectum cancer. In majority (89.8%) of the patients with rectum cancer who received preoperative treatment, conventional chemo-radiotherapy regimen was given. pTNM staging at diagnosis showed that stage III and IV patients were in majority (35.9% and 29.7%, respectively).
CONCLUSION: Colon cancer is more frequent than rectum cancer in Turkey. Colorectal cancer patients are diagnosed at later stages. Most of the cases were operated. Interregional differences for risk factors are worthwhile for evaluation in future trials.

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Year:  2015        PMID: 25835113     DOI: 10.5152/tjg.2015.5685

Source DB:  PubMed          Journal:  Turk J Gastroenterol        ISSN: 1300-4948            Impact factor:   1.852


  10 in total

1.  Colorectal cancer and dysplasia risk of ulcerative colitis patients in a tertiary referral center in Turkey.

Authors:  Nalan Gülşen Ünal; Ömer Özütemiz; Fatih Tekin; İlker Turan; Necla Osmanoğlu
Journal:  Turk J Gastroenterol       Date:  2019-02       Impact factor: 1.852

2.  The Incidence of Malignant Tumors in Environmentally Disadvantaged Regions of Kazakhstan

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Review 5.  Meat and colorectal cancer in Middle Eastern and North African countries: update of literature review.

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6.  The independent and combined effects of selected risk factors and Arg399Gln XRCC1 polymorphism in the risk of colorectal cancer among an Iranian population.

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7.  Colorectal Cancer in North-Eastern Iran: a retrospective, comparative study of early-onset and late-onset cases based on data from the Iranian hereditary colorectal cancer registry.

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Journal:  BMC Cancer       Date:  2022-01-08       Impact factor: 4.430

8.  Trends in colorectal cancer in Iraq over two decades: incidence, mortality, topography and morphology.

Authors:  Salih Ibrahem; Hussien Ahmed; Suhair Zangana
Journal:  Ann Saudi Med       Date:  2022-08-04       Impact factor: 1.707

9.  Single nucleotide polymorphism rs4648298 in miRNAs hsa-miR21 and hsa-miR590 binding site of COX gene is a strong colorectal cancer determinant.

Authors:  Meysam Mosallaei; Miganoosh Simonian; Fateme Ahangari; Maryam Miraghajani; Deniz Mortazavi; Ahmad Reza Salehi; Sharifeh Khosravi; Rasoul Salehi
Journal:  J Gastrointest Oncol       Date:  2018-06

10.  Evaluation of HPV DNA positivity in colorectal cancer patients in Kerman, Southeast Iran

Authors:  Reza Malekpour Afshar; Zeinab Deldar; Hamid Reza Mollaei; Seyed Alimohammad Arabzadeh; Maryam Iranpour
Journal:  Asian Pac J Cancer Prev       Date:  2018-01-27
  10 in total

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