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Literature DB >> 25833846

The PI3K-PKB/Akt pathway.

Brian A Hemmings, David F Restuccia.

Abstract

Year: 2015 PMID： 25833846 PMCID： PMC4382735 DOI： 10.1101/cshperspect.a026609

Source DB: PubMed Journal: Cold Spring Harb Perspect Biol ISSN： 1943-0264 Impact factor: 10.005

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30 in total

1. New bigenic mouse model increases the understanding of genetic synergism in the progression of prostate cancer.

Authors: David J Polman; Douglas K Price; William D Figg
Journal: Cancer Biol Ther Date: 2015 Impact factor: 4.742

2. MicroRNA-21 promotes phosphatase gene and protein kinase B/phosphatidylinositol 3-kinase expression in colorectal cancer.

Authors: Wei-Zhong Sheng; Yu-Sheng Chen; Chuan-Tao Tu; Juan He; Bo Zhang; Wei-Dong Gao
Journal: World J Gastroenterol Date: 2016-06-28 Impact factor: 5.742

3. Acid fibroblast growth factor preserves blood-brain barrier integrity by activating the PI3K-Akt-Rac1 pathway and inhibiting RhoA following traumatic brain injury.

Authors: Fenzan Wu; Zaifeng Chen; Chonghui Tang; Jinjing Zhang; Li Cheng; Hongxia Zuo; Hongyu Zhang; Daqing Chen; Liping Xiang; Jian Xiao; Xiaokun Li; Xinlong Xu; Xiaojie Wei
Journal: Am J Transl Res Date: 2017-03-15 Impact factor: 4.060

Review 4. PI3K: A Crucial Piece in the RAS Signaling Puzzle.

Authors: Agata Adelajda Krygowska; Esther Castellano
Journal: Cold Spring Harb Perspect Med Date: 2018-06-01 Impact factor: 6.915

5. T3 peptide, a fragment of tumstatin, stimulates proliferation and migration of cardiac fibroblasts through activation of Akt signaling pathway.

Authors: Jumpei Yasuda; Kana Fukui; Muneyoshi Okada; Hideyuki Yamawaki
Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 2017-08-07 Impact factor: 3.000

6. MDM2 antagonists overcome intrinsic resistance to CDK4/6 inhibition by inducing p21.

Authors: Anna E Vilgelm; Nabil Saleh; Rebecca Shattuck-Brandt; Kelsie Riemenschneider; Lauren Slesur; Sheau-Chiann Chen; C Andrew Johnson; Jinming Yang; Ashlyn Blevins; Chi Yan; Douglas B Johnson; Rami N Al-Rohil; Ensar Halilovic; Rondi M Kauffmann; Mark Kelley; Gregory D Ayers; Ann Richmond
Journal: Sci Transl Med Date: 2019-08-14 Impact factor: 17.956

The PI3K-PKB/Akt pathway.

1. New bigenic mouse model increases the understanding of genetic synergism in the progression of prostate cancer.

2. MicroRNA-21 promotes phosphatase gene and protein kinase B/phosphatidylinositol 3-kinase expression in colorectal cancer.

3. Acid fibroblast growth factor preserves blood-brain barrier integrity by activating the PI3K-Akt-Rac1 pathway and inhibiting RhoA following traumatic brain injury.

Review 4. PI3K: A Crucial Piece in the RAS Signaling Puzzle.

5. T3 peptide, a fragment of tumstatin, stimulates proliferation and migration of cardiac fibroblasts through activation of Akt signaling pathway.

6. MDM2 antagonists overcome intrinsic resistance to CDK4/6 inhibition by inducing p21.

7. Excess active P13K rescues huntingtin-mediated neuronal cell death but has no effect on axonal transport defects.

Review 8. Insulin regulation of gluconeogenesis.

Review 9. Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?

Review 10. Evolving therapeutic landscape in follicular lymphoma: a look at emerging and investigational therapies.