| Literature DB >> 25833244 |
Karsten Hempel1, David J D Earn2.
Abstract
Infectious diseases spreading in a human population occasionally exhibit sudden transitions in their qualitative dynamics. Previous work has successfully predicted such transitions in New York City's historical measles incidence using the seasonally forced susceptible-infectious-recovered (SIR) model. This work relied on a dataset spanning 45 years (1928-1973), which we have extended to 93 years (1891-1984). We identify additional dynamical transitions in the longer dataset and successfully explain them by analysing attractors and transients of the same mechanistic epidemiological model.Entities:
Keywords: disease dynamics; disease ecology; epidemiology; mathematical biology; measles in New York City; mechanistic modelling
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Year: 2015 PMID: 25833244 PMCID: PMC4424677 DOI: 10.1098/rsif.2015.0024
Source DB: PubMed Journal: J R Soc Interface ISSN: 1742-5662 Impact factor: 4.118