Literature DB >> 25828075

Characteristics of incident female breast cancer in Lebanon, 1990-2013: Descriptive study of 612 cases from a hospital tumor registry.

Georges Chahine1, Elie El Rassy2, Aline Khazzaka3, Khalil Saleh4, Nathalie Rassy5, Nadine Khalife6, David Atallah7.   

Abstract

Despite the fact that breast cancer is a major health issue, very few studies describe its characteristics in the Arab world or the Middle East, particularly in Lebanon. We report in this article a retrospective pilot study of the characteristics of breast cancer in Lebanon. The pathological characteristics of 624 patients diagnosed between 1990 and 2013 randomly chosen from the archives of an oncology clinic affiliated to Hotel Dieu de France Hospital are analyzed. The mean age at diagnosis is 54.6±13.4 years with 43% diagnosed before the age of 50 years. The infiltrative ductal carcinoma represents the major pathological subtype. One third of the tumors had a size of more than 2 cm at diagnosis. Estrogen-receptors are positive in more than 50% of our patients and Her2-neu is overexpresssed in 30%. Luminal A represents 45.5% and the triple negative subgroup constitutes only 8.3%. Breast cancer in Lebanon is evolving to a more indolent disease. Therefore, public awareness and institution of screening programs are required. These programs should be based on national epidemiological data and necessitate the activation of the national cancer registry.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Arab; Breast cancer; Developing countries; Epidemiology; Lebanon; Middle East; Primary healthcare; Primary prevention

Mesh:

Substances:

Year:  2015        PMID: 25828075     DOI: 10.1016/j.canep.2015.03.008

Source DB:  PubMed          Journal:  Cancer Epidemiol        ISSN: 1877-7821            Impact factor:   2.984


  7 in total

Review 1.  Breast cancer screening in developing countries.

Authors:  René Aloísio da Costa Vieira; Gabriele Biller; Gilberto Uemura; Carlos Alberto Ruiz; Maria Paula Curado
Journal:  Clinics (Sao Paulo)       Date:  2017-04       Impact factor: 2.365

2.  Breast Cancer Epidemiology among Lebanese Women: An 11-Year Analysis.

Authors:  Mohamad Y Fares; Hamza A Salhab; Hussein H Khachfe; Hassan M Khachfe
Journal:  Medicina (Kaunas)       Date:  2019-08-10       Impact factor: 2.430

3.  Trends in Breast Cancer Staging at Diagnosis Associated with Screening Campaigns in Lebanon.

Authors:  Christiane J El Khoury; Salim M Adib; Monique Chaaya; Khalil El Asmar; Maya Charafeddine; Nagi S El-Saghir
Journal:  Womens Health Rep (New Rochelle)       Date:  2020-11-26

4.  Frequency and clinical characteristics of HER2 over-expressed breast cancer in Saudi Arabia: a retrospective study.

Authors:  Jamal Zekri; Ahmed Saadeddin; Hulayel Alharbi
Journal:  BMC Womens Health       Date:  2021-01-06       Impact factor: 2.809

5.  Clinical Significance of Breast Cancer Molecular Subtypes and Ki67 Expression as a Predictive Value for Pathological Complete Response following Neoadjuvant Chemotherapy: Experience from a Tertiary Care Center in Lebanon.

Authors:  Ali Atoui; Maroun Bou Zerdan; Ahmad El Mahmoud; Nathalie Chamseddine; Lina Hamad; Hazem I Assi
Journal:  Int J Breast Cancer       Date:  2022-02-12

6.  Untreated chronic lymphocytic leukemia in Lebanese patients: an observational study using standard karyotyping and FISH.

Authors:  Elie El Rassy; Alain Chebly; Rima Korban; Warde Semaan; Ziad Bakouny; Tarek Assi; Hampig Raphael Kourie; Fadi El Karak; Eliane Chouery; Joseph Kattan
Journal:  Int J Hematol Oncol       Date:  2017-12-21

7.  Breast Cancer in Basra Oncology Center: A Clinico- Epidemiological Analysis

Authors:  Rafid A Abood
Journal:  Asian Pac J Cancer Prev       Date:  2018-10-26
  7 in total

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