Literature DB >> 25827663

Colorectal cancer in aged patients. Toward the routine treatment through laparoscopic surgical approach.

R Vecchio, Sergio Marchese, S Famoso, F La Corte, S Marletta, G Leanza, G Zanghì, V Leanza, E Intagliata.   

Abstract

AIM: Colorectal cancer is one of the most common malignancies in general population. The incidence seems to be higher in older age. Surgery remains the treatment of choice and laparoscopic approach offers numerous benefits. We report our personal experience in elderly patients operated on for colorectal cancer with laparoscopic resection. PATIENTS AND METHODS: From January 2003 to September 2013, out of 160 patients aged 65 years or older and operated with minimally invasive techniques, 30 cases affected by colorectal cancer and operated on with laparoscopic approach were analyzed in this study.
RESULTS: Male/female ratio was 1.35 and mean age 72 years. Constipation, weight loss, anemia and rectal bleeding were the most commonly reported symptoms. Lesions involved descending-sigmoid colon in 53% of cases, rectum in 37% and ascending colon in 10%. Among laparoscopic colo-rectal operations laparoscopic left colectomy was the most frequently performed, followed by right colectomy, abdominoperineal resection and Hartmann procedure. Operative times ranged from 3 to 5 hours depending on surgical procedure performed. Mean hospital stay was 6 days (range 4-9). Conversion to open approach occurred only in a case of laparoscopic right colectomy (3%) for uncontrolled bleeding. A single case of mortality was reported. In two cases (7%) anastomotic leakage was observed, conservatively treated in one patient and requiring reoperation in the other one.
CONCLUSIONS: Laparoscopic colorectal surgery is feasible and effective for malignancies in elderly population offering several advantages including immunologic and oncologic ones. However an experienced surgical team is essential in reducing risks and complications.

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Year:  2015        PMID: 25827663      PMCID: PMC4396668     

Source DB:  PubMed          Journal:  G Chir        ISSN: 0391-9005


  25 in total

1.  Laparoscopic left colectomy: from the perfect knowledge of surgical anatomy to the proper surgical technique.

Authors:  R Vecchio; V Gelardi; G Alongi; E Swehli; S Vicari; S Marchese; E Intagliata
Journal:  G Chir       Date:  2010-05

2.  Splenic hilum management during laparoscopic splenectomy.

Authors:  Rosario Vecchio; Salvatore Marchese; Ehab Swehli; Eva Intagliata
Journal:  J Laparoendosc Adv Surg Tech A       Date:  2011-07-21       Impact factor: 1.878

3.  Alterations of cardiovascular performance during laparoscopic colectomy: a combined hemodynamic and echocardiographic analysis.

Authors:  S N Harris; G H Ballantyne; M A Luther; A C Perrino
Journal:  Anesth Analg       Date:  1996-09       Impact factor: 5.108

4.  Long-term results after splenectomy in adult idiopathic thrombocytopenic purpura: comparison between open and laparoscopic procedures.

Authors:  Rosario Vecchio; Salvatore Marchese; Eva Intagliata; Ehab Swehli; Francesco Ferla; Emma Cacciola
Journal:  J Laparoendosc Adv Surg Tech A       Date:  2012-12-11       Impact factor: 1.878

Review 5.  The net immunologic advantage of laparoscopic surgery.

Authors:  Y W Novitsky; D E M Litwin; M P Callery
Journal:  Surg Endosc       Date:  2004-08-26       Impact factor: 4.584

6.  Laparoscopic surgery in the elderly: personal experience in 141 cases.

Authors:  Rosario Vecchio; Valentina Gelardi; Achille Persi; Eva Intagliata
Journal:  J Laparoendosc Adv Surg Tech A       Date:  2010 Jul-Aug       Impact factor: 1.878

7.  Short-term quality-of-life outcomes following laparoscopic-assisted colectomy vs open colectomy for colon cancer: a randomized trial.

Authors:  Jane C Weeks; Heidi Nelson; Shari Gelber; Daniel Sargent; Georgene Schroeder
Journal:  JAMA       Date:  2002-01-16       Impact factor: 56.272

8.  Modifications of coagulation and fibrinolytic parameters in laparoscopic cholecystectomy.

Authors:  R Vecchio; E Cacciola; M Martino; R R Cacciola; B V MacFadyen
Journal:  Surg Endosc       Date:  2002-12-04       Impact factor: 4.584

9.  Haemodynamic and ventilatory changes during laparoscopic cholecystectomy in elderly ASA III patients.

Authors:  K Dhoste; L Lacoste; J Karayan; M S Lehuede; D Thomas; J Fusciardi
Journal:  Can J Anaesth       Date:  1996-08       Impact factor: 5.063

10.  Analysis of laparoscopic port site complications: A descriptive study.

Authors:  Somu Karthik; Alfred Joseph Augustine; Mundunadackal Madhavan Shibumon; Manohar Varadaraya Pai
Journal:  J Minim Access Surg       Date:  2013-04       Impact factor: 1.407

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  10 in total

Review 1.  Topical hemostasis in laparoscopic surgery.

Authors:  R Vecchio; R Catalano; F Basile; C Spataro; M Caputo; E Intagliata
Journal:  G Chir       Date:  2016 Nov-Dec

2.  Surgical drain after open or laparoscopic splenectomy: is it needed or contraindicated?

Authors:  R Vecchio; E Intagliata; S Marchese; S Battaglia; R R Cacciola; E Cacciola
Journal:  G Chir       Date:  2015 May-Jun

3.  A rare case of myeloid sarcoma presenting as anal fissure.

Authors:  R Vecchio; E Intagliata; P F Fiumara; L Villari; S Marchese; E Cacciola
Journal:  G Chir       Date:  2015 Sep-Oct

4.  Neoplastic sigmoid-uterine fistula. An exceptional complication of large intestine cancer.

Authors:  G Zanghì; V Leanza; R Vecchio; A D'Agati; S Cordova; N M Rinzivillo; M Lodato; G Leanza
Journal:  G Chir       Date:  2017 Jan-Feb

5.  Hemocoagulative Modifications after Laparoscopic Surgery at Different Pneumoperitoneum Pressure Settings.

Authors:  Intagliata Eva; Vecchio Rosario; Saitta Cesare; Vizzini Clarissa; Lo Presti Federica; Cacciola Rossella Rosaria; Cacciola Emma; Vecchio Veronica
Journal:  Int J Surg Protoc       Date:  2022-06-14

6.  Subcutaneous cervical emphysema and pneumomediastinum due to a diastatic rupture of the cecum.

Authors:  R Vecchio; E Intagliata; F Basile; C Spataro; G Giulia; V Leanza; S Marchese
Journal:  G Chir       Date:  2015 Nov-Dec

7.  Case Report: Spontaneous cholecystocutaneous fistula, a rare cholethiasis complication.

Authors:  Nunzio Maria Angelo Rinzivillo; Riccardo Danna; Vito Leanza; Melissa Lodato; Salvatore Marchese; Francesco Basile; Guido Nicola Zanghì
Journal:  F1000Res       Date:  2017-09-27

8.  Responsibility of hepatitis C virus in the development of hepatocellular carcinoma: From molecular alterations to possible solutions.

Authors:  Gaetano Bertino; Giulia Malaguarnera; Evelise Frazzetto; Alice Sciuto; Gaetano Inserra; Guido Nicola Zanghì; Michele Malaguarnera
Journal:  World J Hepatol       Date:  2018-06-27

9.  Idiopathic intramural hematoma of the right colon. A case report and review of the literature.

Authors:  Rosario Vecchio; Emma Cacciola; Michele Figuera; Renato Catalano; Giuseppe Giulla; Emanuele Rosario Distefano; Eva Intagliata
Journal:  Int J Surg Case Rep       Date:  2019-05-09

10.  Using Stapler in Laparoscopic Splenectomy Does Not Affect the Risk of Pancreatic Tail Injury.

Authors:  Rosario Vecchio; Emma Cacciola; Eva Intagliata
Journal:  J Indian Assoc Pediatr Surg       Date:  2020-10-27
  10 in total

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