Literature DB >> 25827662

Laparoscopic ultrasound: a surgical "must" for second line intra-operative evaluation of pancreatic cancer resectability.

P Piccolboni, A Settembre, P Angelini, F Esposito, S Palladino, F Corcione.   

Abstract

BACKGROUND: Advanced laparoscopy for pancreatic cancer surgery should include laparoscopic ultrasound (LUS), in order to accurately evaluate resectability and rule out the presence of undetected metastases and/or vascular infiltration. LUS should be done as a preliminary step whenever pre-operative imaging casts doubts on resectability. PATIENTS AND METHODS: We hereby report our experience of 18 consecutive patients, aged 43-76, coming to our attention during a six months period (Jan-Jun 2013), with a diagnosis of pancreas head or body cancer.
RESULTS: LUS allowed to rule out undetected metastases or mesenteric vessels infiltration in 11 patients (61.1%), who were submitted, as previously scheduled, to radical duodeno-pancreatectomy (9 cases) and spleno-caudal pancreatectomy (2 cases). Among the remaining patients, three had been correctly evaluated as non resectable radically at pre-operative work out, and confirmed at LUS, while LUS detected non resectable disease in further 4 patients (22.2%), who underwent palliative procedures. In 2 patients of this group liver micro-metastases were found, while 2 were excluded because of mesenteric vessels infiltration.
CONCLUSIONS: LUS provided a higher level of diagnostic accuracy, allowing in our experience to exclude 4 patients from radical surgery (22.2%). The evaluation of surgical resectability is an issue of crucial importance to decide surgical strategy in pancreas tumor surgery. In our opinion LUS should be considered a mandatory step in laparoscopic approach to pancreatic tumors, to better define disease staging and evaluate resectability.

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Year:  2015        PMID: 25827662      PMCID: PMC4396667     

Source DB:  PubMed          Journal:  G Chir        ISSN: 0391-9005


  14 in total

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2.  Laparoscopic intra-operative ultrasound in liver and pancreas resection: Analysis of 93 cases.

Authors:  D Piccolboni; F Ciccone; A Settembre; F Corcione
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Review 6.  Intraoperative methods to stage and localize pancreatic and duodenal tumors.

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Authors:  Eliza E Long; Jacques Van Dam; Stefanie Weinstein; Brooke Jeffrey; Terry Desser; Jeffrey A Norton
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9.  Is there a role for staging laparoscopy in patients with locally advanced, unresectable pancreatic adenocarcinoma?

Authors:  Margo Shoup; Corinne Winston; Murray F Brennan; Diane Bassman; Kevin C Conlon
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10.  Laparoscopy and laparoscopic ultrasonography in judging the resectability of pancreatic head cancer.

Authors:  Zuo-Wei Zhao; Jin-Yun He; Guang Tan; Hong-Jiang Wang; Ke-Jun Li
Journal:  Hepatobiliary Pancreat Dis Int       Date:  2003-11
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2.  Radiologically occult metastatic pancreatic cancer: how can we avoid unbeneficial resection?

Authors:  Atsushi Oba; Yosuke Inoue; Yoshihiro Ono; Shoichi Irie; Takafumi Sato; Yoshihiro Mise; Hiromichi Ito; Yu Takahashi; Akio Saiura
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