Literature DB >> 25825567

Role of intravenous iron sucrose in correction of anemia in antenatal women with advanced pregnancy.

Avantika Gupta1, Asmita Muthal Rathore2, Usha Manaktala2, Ashutosh Gupta3, Sangeeta Gupta2.   

Abstract

The aim of this study is to observe rise in haematological parameters after treatment with iron sucrose in antenatal patients with moderate anemia with period of gestation 32 to 35 weeks. The study included 45 antenatal patients with period of gestation from 32 to 35 weeks having iron deficiency anemia with haemoglobin levels 7-9 g% and serum ferritin levels less than 12 ng/mL. Intravenous iron sucrose was given in the dose of 200 mg on alternate days, according to the calculated dose. The mean haemoglobin and red blood cell indices were compared on days 7, 14, 21, 28 and at the time of delivery from the baseline value. There was a statistically significant rise in haemoglobin value from baseline on days 14, 21, 28 as well as at the time of delivery (p value <0.0001). The mean rise in haemoglobin values was 0.56 g% on day 14, 1.44 g% on day 21 and 2.0 g% on day 28. At the time of delivery, mean haemoglobin was 11.24 g%. After 28 days of treatment, there was a statistically significant rise in the levels of serum ferritin from 10.33 ± 3.8 ng/mL to 36.89 ± 5.7 ng/mL. Thus, earlier response achieved by iron sucrose can be utilised in the patients presenting at an advanced period of gestation with iron deficiency anemia.

Entities:  

Keywords:  Blood transfusion; Pregnancy near term; Side effects

Year:  2014        PMID: 25825567      PMCID: PMC4375145          DOI: 10.1007/s12288-014-0443-8

Source DB:  PubMed          Journal:  Indian J Hematol Blood Transfus        ISSN: 0971-4502            Impact factor:   0.900


  10 in total

Review 1.  Iron sucrose: the oldest iron therapy becomes new.

Authors:  Jerry Yee; Anatole Besarab
Journal:  Am J Kidney Dis       Date:  2002-12       Impact factor: 8.860

Review 2.  Parenteral iron therapy options.

Authors:  Scott B Silverstein; George M Rodgers
Journal:  Am J Hematol       Date:  2004-05       Impact factor: 10.047

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Journal:  ANNA J       Date:  1999-10

4.  Intravenous versus oral iron for treatment of anemia in pregnancy: a randomized trial.

Authors:  Ragip A Al; Eylem Unlubilgin; Omer Kandemir; Serdar Yalvac; Leyla Cakir; Ali Haberal
Journal:  Obstet Gynecol       Date:  2005-12       Impact factor: 7.661

5.  UK guidelines on the management of iron deficiency in pregnancy.

Authors:  Sue Pavord; Bethan Myers; Susan Robinson; Shubha Allard; Jane Strong; Christina Oppenheimer
Journal:  Br J Haematol       Date:  2012-03       Impact factor: 6.998

6.  Intravenous iron sucrose versus oral iron in treatment of iron deficiency anemia in pregnancy: a randomized clinical trial.

Authors:  Puneet Kaur Kochhar; Asmita Kaundal; Pranay Ghosh
Journal:  J Obstet Gynaecol Res       Date:  2012-08-26       Impact factor: 1.730

7.  A randomised controlled trial to compare intravenous iron sucrose and oral iron in treatment of iron deficiency anemia in pregnancy.

Authors:  Avantika Gupta; Usha Manaktala; Asmita Muthal Rathore
Journal:  Indian J Hematol Blood Transfus       Date:  2013-01-10       Impact factor: 0.900

8.  Use of intravenous iron sucrose for treatment of anaemia in pregnancy.

Authors:  K Kalaivani
Journal:  Indian J Med Res       Date:  2013       Impact factor: 2.375

9.  Intravenous iron sucrose therapy for moderate to severe anaemia in pregnancy.

Authors:  Alka Kriplani; Reeta Mahey; Biswa Bhusan Dash; Vidushi Kulshreshta; Nutan Agarwal; Neerja Bhatla
Journal:  Indian J Med Res       Date:  2013       Impact factor: 2.375

Review 10.  Safety and efficacy of intravenous iron therapy in reducing requirement for allogeneic blood transfusion: systematic review and meta-analysis of randomised clinical trials.

Authors:  Edward Litton; Jing Xiao; Kwok M Ho
Journal:  BMJ       Date:  2013-08-15
  10 in total
  1 in total

1.  Effect of intravenous iron sucrose on hemoglobin level, when administered in a standard-dose, to anemic pregnant women in rural Northern India.

Authors:  Partha Haldar; Shashi Kant; Vikas Yadav; Jitendra Majhi; Sumit Malhotra; Ravneet Kaur; Rakesh Kumar; Arvind Kumar Singh; Siddaiah Archana; Ayush Lohia; Ramashankar Rath; Farhad Ahamed
Journal:  J Family Med Prim Care       Date:  2018 Jul-Aug
  1 in total

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