I-Kuan Wang1, Yu-Kai Cheng2, Cheng-Li Lin3, Chiao-Ling Peng4, Che-Yi Chou5, Chiz-Tzung Chang5, Tzung-Hai Yen6, Chiu-Ching Huang5, Fung-Chang Sung7, Chung Y Hsu8. 1. Department of Internal Medicine and Graduate Institute of Clinical Medical Science, China Medical University College of Medicine, Taichung, Taiwan; Divisions of Nephrology and. 2. Neurosurgery. 3. Management Office for Health Data, China Medical University Hospital, Taichung, Taiwan; 4. Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei, Taiwan; 5. Divisions of Nephrology and. 6. Division of Nephrology, Chang Gung Memorial Hospital, Taipei, Taiwan; and Chang Gung University College of Medicine, Taoyuan, Taiwan. 7. Graduate Institute of Clinical Medical Science, China Medical University College of Medicine, Taichung, Taiwan; Management Office for Health Data, China Medical University Hospital, Taichung, Taiwan; fcsung1008@yahoo.com. 8. Graduate Institute of Clinical Medical Science, China Medical University College of Medicine, Taichung, Taiwan; Department of Neurology, and.
Abstract
BACKGROUND AND OBJECTIVES: This study compared the risk of subdural hematoma (SDH) and subsequent mortality in hemodialysis (HD) and peritoneal dialysis (PD) patients with ESRD. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Claims data were obtained from the National Health Insurance Administration Research Database in Taiwan. This retrospective cohort study comprised 10,136 PD patients and 10,136 HD patients with newly diagnosed ESRD from 1998 to 2010. Patients were matched by propensity score and year of dialysis initiation. Incidence rates and hazard ratios of SDH as well as odds ratios of subsequent 30-day deaths from SDH were evaluated from the date of the first dialysis session to the date when SDH was diagnosed, or the date of renal transplantation, death, withdraw from insurance, or the end of the follow-up period (December 31, 2011). RESULTS: Median (25th percentile, 75th percentile) follow-up times for SDH events were 3.61 years (1.91, 6.33) and 3.33 years (1.83, 5.66) in the HD and PD cohorts, respectively. The overall SDH incidence rate (95% confidence interval [95% CI]) was 61.4% higher in the HD cohort than in the PD cohort (34.7 [95% CI, 31.4 to 35.4] versus 21.5 [95% CI, 20.2 to 22.9] per 10,000 person-years, with an adjusted hazard ratio of 1.62 [95% CI, 1.17 to 2.33]). Approximately 152 of 253 (60%) of SDH events were associated with trauma. Subsequent 30-day SDH-related mortality was not statistically higher in HD patients than in PD patients (29.1% versus 25.3%; adjusted odds ratio, 1.30; 95% CI, 0.70 to 2.41). CONCLUSIONS: HD patients have a higher risk of developing SDH than PD patients. Both patient groups have a high risk of mortality. Routine education on fall prevention is needed for dialysis patients.
BACKGROUND AND OBJECTIVES: This study compared the risk of subdural hematoma (SDH) and subsequent mortality in hemodialysis (HD) and peritoneal dialysis (PD) patients with ESRD. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Claims data were obtained from the National Health Insurance Administration Research Database in Taiwan. This retrospective cohort study comprised 10,136 PDpatients and 10,136 HDpatients with newly diagnosed ESRD from 1998 to 2010. Patients were matched by propensity score and year of dialysis initiation. Incidence rates and hazard ratios of SDH as well as odds ratios of subsequent 30-day deaths from SDH were evaluated from the date of the first dialysis session to the date when SDH was diagnosed, or the date of renal transplantation, death, withdraw from insurance, or the end of the follow-up period (December 31, 2011). RESULTS: Median (25th percentile, 75th percentile) follow-up times for SDH events were 3.61 years (1.91, 6.33) and 3.33 years (1.83, 5.66) in the HD and PD cohorts, respectively. The overall SDH incidence rate (95% confidence interval [95% CI]) was 61.4% higher in the HD cohort than in the PD cohort (34.7 [95% CI, 31.4 to 35.4] versus 21.5 [95% CI, 20.2 to 22.9] per 10,000 person-years, with an adjusted hazard ratio of 1.62 [95% CI, 1.17 to 2.33]). Approximately 152 of 253 (60%) of SDH events were associated with trauma. Subsequent 30-day SDH-related mortality was not statistically higher in HDpatients than in PDpatients (29.1% versus 25.3%; adjusted odds ratio, 1.30; 95% CI, 0.70 to 2.41). CONCLUSIONS:HDpatients have a higher risk of developing SDH than PDpatients. Both patient groups have a high risk of mortality. Routine education on fall prevention is needed for dialysis patients.
Authors: Anita van Eck van der Sluijs; Alferso C Abrahams; Maarten B Rookmaaker; Marianne C Verhaar; Willem Jan W Bos; Peter J Blankestijn; Friedo W Dekker; Merel van Diepen; Gurbey Ocak Journal: Nephrol Dial Transplant Date: 2021-01-01 Impact factor: 5.992
Authors: Ahmed Fayed; Ayman Tarek; Mohamed I Refaat; Sameh Abouzeid; Sohail Abdul Salim; Lajos Zsom; Tibor Fülöp; Karim M Soliman; Mohamed A Elmallawany Journal: Ren Fail Date: 2021-12 Impact factor: 2.606