Cyrus S H Ho1, Adrian Mondry2. 1. Department of Psychological Medicine, National University Hospital, National University Health System, Singapore. Electronic address: su_hui_ho@nuhs.edu.sg. 2. Division of General Medicine, National University Hospital, National University Health System, Singapore.
Abstract
OBJECTIVE: To describe an Asian patient with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) presenting with schizophreniform organic psychosis. METHODS: Case report. RESULTS: We report a case of CADASIL in an Asian female presenting with frank psychotic symptoms. After resolution of her psychosis, she showed persistent distractibility, which indicated signs of cognitive impairment. CONCLUSION: Although neuropsychiatric symptoms are commonly present in this disorder, psychotic symptoms are rare and should be recognized. There is a need for timely diagnosis and management of this disorder.
OBJECTIVE: To describe an Asian patient with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) presenting with schizophreniform organic psychosis. METHODS: Case report. RESULTS: We report a case of CADASIL in an Asian female presenting with frank psychotic symptoms. After resolution of her psychosis, she showed persistent distractibility, which indicated signs of cognitive impairment. CONCLUSION: Although neuropsychiatric symptoms are commonly present in this disorder, psychotic symptoms are rare and should be recognized. There is a need for timely diagnosis and management of this disorder.
Authors: Ilaria Di Donato; Silvia Bianchi; Nicola De Stefano; Martin Dichgans; Maria Teresa Dotti; Marco Duering; Eric Jouvent; Amos D Korczyn; Saskia A J Lesnik-Oberstein; Alessandro Malandrini; Hugh S Markus; Leonardo Pantoni; Silvana Penco; Alessandra Rufa; Osman Sinanović; Dragan Stojanov; Antonio Federico Journal: BMC Med Date: 2017-02-24 Impact factor: 8.775