Literature DB >> 2582243

Glycoprotein PAS-0 from the milk fat globule membrane carries antigenic determinants for epithelial membrane antigen.

M G Ormerod, J McIlhinney, K Steele, M Shimizu.   

Abstract

Epithelial membrane antigen (EMA) can be found in human tissues using antisera raised against defatted human cream. PAS-0 is a glycoprotein which has been extracted from human milk fat globule membranes. Using a polyclonal antiserum and a series of monoclonal antibodies, we have shown that the major antigenic determinant for EMA is carried by PAS-0. A more detailed comparison of the two glycoproteins has been made by establishing a set of radioimmunoassays using the different antibodies.

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Year:  1985        PMID： 2582243     DOI： 10.1016/0161-5890(85)90160-9

Source DB:  PubMed          Journal:  Mol Immunol        ISSN： 0161-5890            Impact factor:   4.407


  6 in total

1.  Critical evaluation of monoclonal antibody staining in breast carcinoma.

Authors:  D M Parham; G Coghill; A J Robertson
Journal:  J Clin Pathol       Date:  1989-08       Impact factor: 3.411

2.  Analysis of the tumour-associated antigen TAG-12 by monoclonal antibody 7A9 in normal, benign and malignant mammary tissues.

Authors:  M Werner; R von Wasielewski; J Bernhards; A Georgii
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1990

3.  Human tumor and normal tissue reactivity of the anti-(breast cancer) monoclonal antibody BA-Br-3 and its similarity to the anti-(epithelial membrane antigen) monoclonal antibody E29.

Authors:  S K Liao; R E Flahart; B Kimbro; L Horton; R K Oldham; J Hilgers; R van der Gaag
Journal:  Cancer Immunol Immunother       Date:  1990       Impact factor: 6.968

4.  High-Mr glycoprotein profiles in human milk serum and fat-globule membrane.

Authors:  M Shimizu; K Yamauchi; Y Miyauchi; T Sakurai; K Tokugawa; R A McIlhinney
Journal:  Biochem J       Date:  1986-02-01       Impact factor: 3.857

5.  Epitope analysis of monoclonal antibody NCRC-11 defined antigen isolated from human ovarian and breast carcinomas.

Authors:  M R Price; S Edwards; M Powell; R W Baldwin
Journal:  Br J Cancer       Date:  1986-09       Impact factor: 7.640

6.  Purification and biochemical characterisation of a novel breast carcinoma associated mucin-like glycoprotein defined by antibody 3E1.2.

Authors:  S A Stacker; J J Tjandra; P X Xing; I D Walker; C H Thompson; I F McKenzie
Journal:  Br J Cancer       Date:  1989-04       Impact factor: 7.640
  6 in total

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