Literature DB >> 2581522

Fibrous bodies in growth hormone-secreting adenomas contain cytokeratin filaments.

P E Neumann, J E Goldman, D S Horoupian, M A Hess.   

Abstract

Fibrous bodies in growth hormone-secreting adenomas were studied by immunocytochemistry using an anti-cytokeratin antiserum. Fibrous bodies are a feature of acidophil and chromophobe adenomas and are usually associated with acromegaly. Ultrastructural examination revealed round juxtanuclear filamentous aggregates, composed of 8-nm filaments and other organelles. This study demonstrated that the intermediate filaments of fibrous bodies belong to the cytokeratin class. The etiology and significance of these filamentous aggregates remain obscure.

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Year:  1985        PMID： 2581522

Source DB:  PubMed          Journal:  Arch Pathol Lab Med        ISSN： 0003-9985            Impact factor:   5.534


  12 in total

1.  Pancreatic endocrine tumour with cytoplasmic keratin whorls. Is the term "rhabdoid" appropriate?

Authors:  R Chetty; S L Asa
Journal:  J Clin Pathol       Date:  2004-10       Impact factor: 3.411

2.  Unusual type of growth hormone-producing pituitary tumor in acromegaly.

Authors:  Satoshi Yamagata; Kazunori Kageyama; Satoru Sakihara; Shozo Yamada; Shinobu Takayasu; Shinji Chikazawa; Naoko Inoshita; Toshiaki Sano; Toshihiro Suda
Journal:  Endocr Pathol       Date:  2012-09       Impact factor: 3.943

3.  Immunolocalisation of cytokeratins in the normal and neoplastic human pituitary gland.

Authors:  J W Ironside; J A Royds; A A Jefferson; W R Timperley
Journal:  J Neurol Neurosurg Psychiatry       Date:  1987-01       Impact factor: 10.154

4.  Cytokeratin distribution and functional properties of growth hormone-producing pituitary adenomas.

Authors:  Toshiaki Sano; Shozo Yamada; Takashi Hi Rose; Kazuo Hizawa
Journal:  Endocr Pathol       Date:  1994-06       Impact factor: 3.943

5.  Growth hormone tumor histological subtypes predict response to surgical and medical therapy.

Authors:  Katja Kiseljak-Vassiliades; Nichole E Carlson; Manuel T Borges; B K Kleinschmidt-DeMasters; Kevin O Lillehei; Janice M Kerr; Margaret E Wierman
Journal:  Endocrine       Date:  2014-08-17       Impact factor: 3.633

6.  Bronchial carcinoid with paranuclear fibrillary inclusions related to cytokeratins and vimentin.

Authors:  M Barbareschi; B Frigo; S Cristina; L Valentini; E Leonardi; L Mosca
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1989

7.  Clinical, biological, radiological, and pathological comparison of sparsely and densely granulated somatotroph adenomas: a single center experience from a cohort of 131 patients with acromegaly.

Authors:  Amy A Swanson; Dana Erickson; Diane Mary Donegan; Sarah M Jenkins; Jamie J Van Gompel; John L D Atkinson; Bradley J Erickson; Caterina Giannini
Journal:  Pituitary       Date:  2020-10-19       Impact factor: 4.107

8.  Downregulation of E-cadherin and its undercoat proteins in pituitary growth hormone cell adenomas with prominent fibrous bodies.

Authors:  Bing Xu; Toshiaki Sano; Katsuhiko Yoshimoto; Shozo Yamada
Journal:  Endocr Pathol       Date:  2002       Impact factor: 3.943

9.  Clinicopathological features of growth hormone-producing pituitary adenomas: difference among various types defined by cytokeratin distribution pattern including a transitional form.

Authors:  Abdulkader Obari; Toshiaki Sano; Kenichi Ohyama; Eiji Kudo; Zhi Rong Qian; Akiko Yoneda; Nasim Rayhan; Muhammad Mustafizur Rahman; Shozo Yamada
Journal:  Endocr Pathol       Date:  2008       Impact factor: 3.943

10.  A histopathological and ultrastructural study of eccrine porocarcinoma with special reference to its subtypes.

Authors:  O Yamamoto; J Haratake; S Yokoyama; S Imayama; M Asahi
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1992
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