Literature DB >> 25813034

Double trouble: should double embryo transfer be banned?

Dominic Wilkinson1, G Owen Schaefer, Kelton Tremellen, Julian Savulescu.   

Abstract

What role should legislation or policy play in avoiding the complications of in-vitro fertilization? In this article, we focus on single versus double embryo transfer, and assess three arguments in favour of mandatory single embryo transfer: risks to the mother, risks to resultant children, and costs to society. We highlight significant ethical concerns about each of these. Reproductive autonomy and non-paternalism are strong enough to outweigh the health concerns for the woman. Complications due to non-identity cast doubt on the extent to which children are harmed. Twinning may offer an overall benefit rather than burden to society. Finally, including the future health costs for children (not yet born) in reproductive policy is inconsistent with other decisions. We conclude that mandatory single embryo transfer is not justified and that a number of countries should reconsider their current embryo transfer policy.

Entities:  

Mesh:

Year:  2015        PMID: 25813034     DOI: 10.1007/s11017-015-9324-x

Source DB:  PubMed          Journal:  Theor Med Bioeth        ISSN: 1386-7415


  52 in total

1.  Cumulative live-birth rates in a trial of single-embryo or double-embryo transfer.

Authors:  Ann Thurin-Kjellberg; Catharina Olivius; Christina Bergh
Journal:  N Engl J Med       Date:  2009-10-29       Impact factor: 91.245

2.  The epidemic of multiple gestations and neonatal intensive care unit use: the cost of irresponsibility.

Authors:  Annie Janvier; Bridget Spelke; Keith J Barrington
Journal:  J Pediatr       Date:  2011-04-13       Impact factor: 4.406

3.  Effect of age on decisions about the numbers of embryos to transfer in assisted conception: a prospective study.

Authors:  Debbie A Lawlor; Scott M Nelson
Journal:  Lancet       Date:  2012-01-12       Impact factor: 79.321

4.  Why does it matter how we regulate the use of human body parts?

Authors:  Imogen Goold
Journal:  J Med Ethics       Date:  2014-01       Impact factor: 2.903

5.  Randomized single versus double embryo transfer: obstetric and paediatric outcome and a cost-effectiveness analysis.

Authors:  Ann Thurin Kjellberg; Per Carlsson; Christina Bergh
Journal:  Hum Reprod       Date:  2005-09-19       Impact factor: 6.918

6.  Refuting a misguided campaign against the goal of single-embryo transfer and singleton birth in assisted reproduction.

Authors:  Robert J Stillman; Kevin S Richter; Howard W Jones
Journal:  Hum Reprod       Date:  2013-07-30       Impact factor: 6.918

7.  The impact of legally restricted embryo transfer and reimbursement policy on cumulative delivery rate after treatment with assisted reproduction technology.

Authors:  K Peeraer; S Debrock; A Laenen; P De Loecker; C Spiessens; D De Neubourg; T M D'Hooghe
Journal:  Hum Reprod       Date:  2013-11-26       Impact factor: 6.918

8.  Elective single-embryo transfer versus double-embryo transfer in in vitro fertilization.

Authors:  Ann Thurin; Jon Hausken; Torbjörn Hillensjö; Barbara Jablonowska; Anja Pinborg; Annika Strandell; Christina Bergh
Journal:  N Engl J Med       Date:  2004-12-02       Impact factor: 91.245

9.  Cesarean section on maternal request: reasons for the request, self-estimated health, expectations, experience of birth and signs of depression among first-time mothers.

Authors:  Ingela Wiklund; Gunnar Edman; Ellika Andolf
Journal:  Acta Obstet Gynecol Scand       Date:  2007       Impact factor: 3.636

10.  Neonatal and maternal outcomes comparing women undergoing two in vitro fertilization (IVF) singleton pregnancies and women undergoing one IVF twin pregnancy.

Authors:  Antonina Sazonova; Karin Källen; Ann Thurin-Kjellberg; Ulla-Britt Wennerholm; Christina Bergh
Journal:  Fertil Steril       Date:  2012-12-07       Impact factor: 7.329

View more
  3 in total

Review 1.  Next-generation molecular diagnosis: single-cell sequencing from bench to bedside.

Authors:  Wanjun Zhu; Xiao-Yan Zhang; Sadie L Marjani; Jialing Zhang; Wengeng Zhang; Shixiu Wu; Xinghua Pan
Journal:  Cell Mol Life Sci       Date:  2016-10-13       Impact factor: 9.261

2.  Is mandating elective single embryo transfer ethically justifiable in young women?

Authors:  Kelton Tremellen; Dominic Wilkinson; Julian Savulescu
Journal:  Reprod Biomed Soc Online       Date:  2016-02-18

3.  Is the non-identity problem relevant to public health and policy? An online survey.

Authors:  Keyur Doolabh; Lucius Caviola; Julian Savulescu; Michael J Selgelid; Dominic Wilkinson
Journal:  BMC Med Ethics       Date:  2019-07-05       Impact factor: 2.652

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.