| Literature DB >> 25806316 |
Abstract
Adjuvant chemotherapy has been established as a standard for patients with completely resected non-small cell lung cancer (NSCLC). Adjuvant chemotherapy increased the 5-year survival rates by 4% to 15% within randomized trials and, based on a meta-analysis of five cisplatin-based trials, by 5.4%. Adjuvant chemotherapy consists of a cisplatin-based doublet, preferentially cisplatin plus vinorelbine. Future improvements in outcome of adjuvant therapy are expected by customized chemotherapy and the integration of targeted therapies or immunotherapy.Entities:
Keywords: Adjuvant; chemotherapy; non-small cell lung cancer (NSCLC); resection
Year: 2014 PMID: 25806316 PMCID: PMC4367797 DOI: 10.3978/j.issn.2218-6751.2014.09.13
Source DB: PubMed Journal: Transl Lung Cancer Res ISSN: 2218-6751