Deborah K L Tan1, Wan Ting Tay1, Cordelia Chan1, Donald T H Tan1, Jodhbir S Mehta2. 1. From the Singapore Eye Research Institute (D.K.L. Tan, Tay, Chan, D.T.H. Tan, Mehta), the Department of Ophthalmology (D.T.H. Tan), Yong Loo Lin School of Medicine, National University of Singapore, the Singapore National Eye Center (D.K.L. Tan, Chan, D.T.H. Tan), the Department of Clinical Sciences (Mehta), Duke-NUS Graduate Medical School, and the Lee Kong Chian School of Medicine (D.T.H. Tan), Nanyang Technological University, Singapore. 2. From the Singapore Eye Research Institute (D.K.L. Tan, Tay, Chan, D.T.H. Tan, Mehta), the Department of Ophthalmology (D.T.H. Tan), Yong Loo Lin School of Medicine, National University of Singapore, the Singapore National Eye Center (D.K.L. Tan, Chan, D.T.H. Tan), the Department of Clinical Sciences (Mehta), Duke-NUS Graduate Medical School, and the Lee Kong Chian School of Medicine (D.T.H. Tan), Nanyang Technological University, Singapore. Electronic address: jodmehta@gmail.com.
Abstract
PURPOSE: To evaluate and compare changes in contrast sensitivity and ocular higher-order aberrations (HOAs) after femtosecond lenticule extraction (FLEx) and pseudo small-incision lenticule extraction (SMILE). SETTING: Singapore National Eye Centre, Singapore. DESIGN: Retrospective case series. METHOD: Patients had femtosecond lenticule extraction (Group 1) or pseudo small-incision lenticule extraction (Group 2) between March 2010 and December 2011. The main outcome measures were manifest refraction, HOAs, and contrast sensitivity 1, 3, 6, and 12 months postoperatively. RESULTS: Fifty-two consecutive patients (102 eyes) were recruited, 21 patients (42 eyes) in Group 1 and the 31 patients (60 eyes) in Group 2. The uncorrected and corrected distance visual acuities were significantly better in Group 2 than in Group 1 at 12 months (P = .032). There was no significant increase in 3rd- or 4th-order aberrations at 1 year and no significant difference between the 2 groups preoperatively or postoperatively. At 1 year, there was a significant increase in mesopic contrast sensitivity in Group 2 at 1.5 cycles per degree (cpd) (P = .008) that was not found in Group 1, and photopic contrast sensitivity at 6.0 cpd was higher in Group 2 (P = .027). CONCLUSIONS: These results indicate that refractive lenticule extraction is safe and effective with no significant induction of HOAs or deterioration in contrast sensitivity at 1 year. Induction of HOAs was not significantly different between both variants of refractive lenticule extraction. However, there was significant improvement in photopic contrast sensitivity after pseudo small-incision lenticule extraction, which persisted through 1 year. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned.
PURPOSE: To evaluate and compare changes in contrast sensitivity and ocular higher-order aberrations (HOAs) after femtosecond lenticule extraction (FLEx) and pseudo small-incision lenticule extraction (SMILE). SETTING: Singapore National Eye Centre, Singapore. DESIGN: Retrospective case series. METHOD:Patients had femtosecond lenticule extraction (Group 1) or pseudo small-incision lenticule extraction (Group 2) between March 2010 and December 2011. The main outcome measures were manifest refraction, HOAs, and contrast sensitivity 1, 3, 6, and 12 months postoperatively. RESULTS: Fifty-two consecutive patients (102 eyes) were recruited, 21 patients (42 eyes) in Group 1 and the 31 patients (60 eyes) in Group 2. The uncorrected and corrected distance visual acuities were significantly better in Group 2 than in Group 1 at 12 months (P = .032). There was no significant increase in 3rd- or 4th-order aberrations at 1 year and no significant difference between the 2 groups preoperatively or postoperatively. At 1 year, there was a significant increase in mesopic contrast sensitivity in Group 2 at 1.5 cycles per degree (cpd) (P = .008) that was not found in Group 1, and photopic contrast sensitivity at 6.0 cpd was higher in Group 2 (P = .027). CONCLUSIONS: These results indicate that refractive lenticule extraction is safe and effective with no significant induction of HOAs or deterioration in contrast sensitivity at 1 year. Induction of HOAs was not significantly different between both variants of refractive lenticule extraction. However, there was significant improvement in photopic contrast sensitivity after pseudo small-incision lenticule extraction, which persisted through 1 year. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned.
Authors: Yu-Chi Liu; Geraint P Williams; Ben L George; Yu Qiang Soh; Xin Yi Seah; Gary Swee Lim Peh; Gary Hin Fai Yam; Jodhbir S Mehta Journal: Mol Vis Date: 2017-10-27 Impact factor: 2.367
Authors: Hon Shing Ong; Mohamed Farook; Benjamin Boon Chuan Tan; Geraint P Williams; Marcony R Santhiago; Jodhbir S Mehta Journal: Clin Ophthalmol Date: 2019-10-14