Literature DB >> 25797842

Investigating the psychosocial determinants of child health in Africa: The Drakenstein Child Health Study.

D J Stein1, N Koen2, K A Donald3, C M Adnams4, S Koopowitz4, C Lund4, A Marais4, B Myers5, A Roos6, K Sorsdahl4, M Stern4, M Tomlinson7, C van der Westhuizen4, B Vythilingum4, L Myer8, W Barnett3, K Brittain3, H J Zar3.   

Abstract

BACKGROUND: Early life psychobiological and psychosocial factors play a key role in influencing child health outcomes. Longitudinal studies may help elucidate the relevant risk and resilience profiles, and the underlying mechanisms that impact on child health, but there is a paucity of birth cohort data from low and middle-income countries (LMIC). We describe the rationale for and present baseline findings from the psychosocial component of the Drakenstein Child Health Study (DCHS).
METHODS: We review the psychosocial measures used in the DCHS, a multidisciplinary birth cohort study in a peri-urban area in South Africa, and provide initial data on psychological distress, depression, substance use, and exposure to traumatic stressors and intimate partner violence (IPV). These and other measures will be assessed longitudinally in mothers in order to investigate associations with child neurodevelopmental and health outcomes.
RESULTS: Baseline psychosocial data is presented for mothers (n=634) and fathers (n=75) who have completed antenatal assessments to date. The sample of pregnant mothers is characterized by multiple psychosocial risk factors, including a high prevalence of psychological distress and depression, high levels of substance use, and high exposure to traumatic stressors and IPV. DISCUSSION: These data are consistent with prior South African studies which have documented a high prevalence of a multitude of risk factors during pregnancy. Further longitudinal assessment of mothers and children may clarify the underlying psychobiological and psychosocial mechanisms which impact on child health, and so inform clinical and public health interventions appropriate to the South African and other LMIC contexts.
Copyright © 2015 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Birth cohort; Child health; Depression; Intimate partner violence; South Africa; Substance use

Mesh:

Year:  2015        PMID: 25797842      PMCID: PMC4556362          DOI: 10.1016/j.jneumeth.2015.03.016

Source DB:  PubMed          Journal:  J Neurosci Methods        ISSN: 0165-0270            Impact factor:   2.390


  49 in total

Review 1.  Prenatal and postpartum maternal psychological distress and infant development: a systematic review.

Authors:  Dawn Kingston; Suzanne Tough; Heather Whitfield
Journal:  Child Psychiatry Hum Dev       Date:  2012-10

2.  Mechanisms linking early life stress to adult health outcomes.

Authors:  Shelley E Taylor
Journal:  Proc Natl Acad Sci U S A       Date:  2010-05-04       Impact factor: 11.205

Review 3.  Child development: risk factors for adverse outcomes in developing countries.

Authors:  Susan P Walker; Theodore D Wachs; Julie Meeks Gardner; Betsy Lozoff; Gail A Wasserman; Ernesto Pollitt; Julie A Carter
Journal:  Lancet       Date:  2007-01-13       Impact factor: 79.321

4.  Translation and cross-cultural adaptation of a mental health battery in an African setting.

Authors:  J Smit; C E van den Berg; L-G Bekker; S Seedat; D J Stein
Journal:  Afr Health Sci       Date:  2006-12       Impact factor: 0.927

5.  The relationship between depression, anxiety and medication adherence among patients receiving antiretroviral treatment in South Africa.

Authors:  Adriaan Nel; Ashraf Kagee
Journal:  AIDS Care       Date:  2012-12-11

Review 6.  Neurobiological and psychiatric consequences of child abuse and neglect.

Authors:  Christine Heim; Margaret Shugart; W Edward Craighead; Charles B Nemeroff
Journal:  Dev Psychobiol       Date:  2010-11       Impact factor: 3.038

7.  Intimate partner violence: causes and prevention.

Authors:  Rachel Jewkes
Journal:  Lancet       Date:  2002-04-20       Impact factor: 79.321

8.  Social determinants of psychological distress in a nationally-representative sample of South African adults.

Authors:  Landon Myer; Dan J Stein; Anna Grimsrud; Soraya Seedat; David R Williams
Journal:  Soc Sci Med       Date:  2008-03-04       Impact factor: 4.634

9.  Multiple risk factors during pregnancy in South Africa: the need for a horizontal approach to perinatal care.

Authors:  Mark Tomlinson; Mary J O'Connor; Ingrid M le Roux; Jacqueline Stewart; Nokwanele Mbewu; Jessica Harwood; Mary Jane Rotheram-Borus
Journal:  Prev Sci       Date:  2014-06

10.  Alcohol and Other Drug Use during Pregnancy among Women Attending Midwife Obstetric Units in the Cape Metropole, South Africa.

Authors:  Petal Petersen Williams; Esmé Jordaan; Catherine Mathews; Carl Lombard; Charles D H Parry
Journal:  Adv Prev Med       Date:  2014-02-03
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  58 in total

1.  Investigating tangible and mental resources as predictors of perceived household food insecurity during pregnancy among women in a South African birth cohort study.

Authors:  Jennifer A Pellowski; Whitney Barnett; Caroline C Kuo; Nastassja Koen; Heather J Zar; Dan J Stein
Journal:  Soc Sci Med       Date:  2017-06-20       Impact factor: 4.634

2.  Mental health predictors of breastfeeding initiation and continuation among HIV infected and uninfected women in a South African birth cohort study.

Authors:  Eileen Thomas; Caroline Kuo; Sophie Cohen; Jacqueline Hoare; Natassja Koen; Whitney Barnett; Heather J Zar; Dan J Stein
Journal:  Prev Med       Date:  2017-07-08       Impact factor: 4.018

3.  Interhemispheric Functional Brain Connectivity in Neonates with Prenatal Alcohol Exposure: Preliminary Findings.

Authors:  Kirsten A Donald; Jonathan C Ipser; Fleur M Howells; Annerine Roos; Jean-Paul Fouche; Edward P Riley; Nastassja Koen; Roger P Woods; Bharat Biswal; Heather J Zar; Katherine L Narr; Dan J Stein
Journal:  Alcohol Clin Exp Res       Date:  2016-01       Impact factor: 3.455

4.  Maternal posttraumatic stress disorder and infant developmental outcomes in a South African birth cohort study.

Authors:  Nastassja Koen; Kirsty Brittain; Kirsten A Donald; Whitney Barnett; Sheri Koopowitz; Karen Maré; Heather J Zar; Dan J Stein
Journal:  Psychol Trauma       Date:  2017-05

5.  Alcohol exposure in utero is associated with decreased gray matter volume in neonates.

Authors:  Kirsten A Donald; J P Fouche; Annerine Roos; Nastassja Koen; Fleur M Howells; Edward P Riley; Roger P Woods; Heather J Zar; Katherine L Narr; Dan J Stein
Journal:  Metab Brain Dis       Date:  2015-11-29       Impact factor: 3.584

6.  Lung Function in African Infants in the Drakenstein Child Health Study. Impact of Lower Respiratory Tract Illness.

Authors:  Diane M Gray; Lidija Turkovic; Lauren Willemse; Ane Visagie; Aneesa Vanker; Dan J Stein; Peter D Sly; Graham L Hall; Heather J Zar
Journal:  Am J Respir Crit Care Med       Date:  2017-01-15       Impact factor: 21.405

Review 7.  Challenges of access to kidney care for children in low-resource settings.

Authors:  Mignon McCulloch; Valerie A Luyckx; Brett Cullis; Simon J Davies; Fredric O Finkelstein; Hui Kim Yap; John Feehally; William E Smoyer
Journal:  Nat Rev Nephrol       Date:  2020-10-01       Impact factor: 28.314

8.  Prenatal alcohol exposure is associated with early motor, but not language development in a South African cohort.

Authors:  Gaironeesa Hendricks; Susan Malcolm-Smith; Dan J Stein; Heather J Zar; Catherine J Wedderburn; Raymond T Nhapi; Tawanda Chivese; Colleen M Adnams; Kirsten A Donald
Journal:  Acta Neuropsychiatr       Date:  2020-01-06       Impact factor: 3.403

9.  Reduced glutamate in white matter of male neonates exposed to alcohol in utero: a (1)H-magnetic resonance spectroscopy study.

Authors:  F M Howells; K A Donald; A Roos; R P Woods; H J Zar; K L Narr; D J Stein
Journal:  Metab Brain Dis       Date:  2016-06-16       Impact factor: 3.584

10.  Association of maternal prenatal psychological stressors and distress with maternal and early infant faecal bacterial profile.

Authors:  Petrus J W Naudé; Shantelle Claassen-Weitz; Sugnet Gardner-Lubbe; Gerrit Botha; Mamadou Kaba; Heather J Zar; Mark P Nicol; Dan J Stein
Journal:  Acta Neuropsychiatr       Date:  2019-12-20       Impact factor: 3.403

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