| Literature DB >> 25796424 |
Timothy Pok Chi Yeung1, Glenn Bauman2, Slav Yartsev3, Enrico Fainardi4, David Macdonald5, Ting-Yim Lee6.
Abstract
Dynamic perfusion CT (PCT) is an imaging technique for assessing the vascular supply and hemodynamics of brain tumors by measuring blood flow, blood volume, and permeability-surface area product. These PCT parameters provide information complementary to histopathologic assessments and have been used for grading brain tumors, distinguishing high-grade gliomas from other brain lesions, differentiating true progression from post-treatment effects, and predicting prognosis after treatments. In this review, the basic principles of PCT are described, and applications of PCT of brain tumors are discussed. The advantages and current challenges, along with possible solutions, of PCT are presented.Entities:
Keywords: Adiabatic Approximation of Johnson and Wilson Model; Blood flow; Blood volume; Brain tumor; Dynamic perfusion CT; Permeability-surface area product
Mesh：
Year: 2015 PMID： 25796424 DOI： 10.1016/j.ejrad.2015.02.012
Source DB: PubMed Journal: Eur J Radiol ISSN： 0720-048X Impact factor: 3.528