Literature DB >> 25795242

LQT1-phenotypes in hiPSC: Are we measuring the right thing?

Torsten Christ1, András Horvath2, Thomas Eschenhagen2.   

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Year:  2015        PMID： 25795242      PMCID： PMC4413273          DOI： 10.1073/pnas.1503347112

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  5 in total

1.  K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current.

Authors:  J Barhanin; F Lesage; E Guillemare; M Fink; M Lazdunski; G Romey
Journal:  Nature       Date:  1996-11-07       Impact factor: 49.962

2.  Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel.

Authors:  M C Sanguinetti; M E Curran; A Zou; J Shen; P S Spector; D L Atkinson; M T Keating
Journal:  Nature       Date:  1996-11-07       Impact factor: 49.962

3.  Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle.

Authors:  Norbert Jost; László Virág; Miklós Bitay; János Takács; Csaba Lengyel; Péter Biliczki; Zsolt Nagy; Gábor Bogáts; David A Lathrop; Julius G Papp; András Varró
Journal:  Circulation       Date:  2005-08-29       Impact factor: 29.690

4.  Probing the contribution of IKs to canine ventricular repolarization: key role for beta-adrenergic receptor stimulation.

Authors:  Paul G A Volders; Milan Stengl; Jurren M van Opstal; Uwe Gerlach; Roel L H M G Spätjens; Jet D M Beekman; Karin R Sipido; Marc A Vos
Journal:  Circulation       Date:  2003-05-19       Impact factor: 29.690

5.  Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue.

Authors:  Miao Zhang; Cristina D'Aniello; Arie O Verkerk; Eva Wrobel; Stefan Frank; Dorien Ward-van Oostwaard; Ilaria Piccini; Christian Freund; Jyoti Rao; Guiscard Seebohm; Douwe E Atsma; Eric Schulze-Bahr; Christine L Mummery; Boris Greber; Milena Bellin
Journal:  Proc Natl Acad Sci U S A       Date:  2014-12-01       Impact factor: 11.205
  5 in total
  8 in total

1.  Reply to Christ et al.: LQT1 and JLNS phenotypes in hiPSC-derived cardiomyocytes are due to KCNQ1 mutations.

Authors:  Boris Greber; Arie O Verkerk; Guiscard Seebohm; Christine L Mummery; Milena Bellin
Journal:  Proc Natl Acad Sci U S A       Date:  2015-03-20       Impact factor: 11.205

2.  Simplified Footprint-Free Cas9/CRISPR Editing of Cardiac-Associated Genes in Human Pluripotent Stem Cells.

Authors:  Alexander Kondrashov; Minh Duc Hoang; James G W Smith; Jamie R Bhagwan; Gary Duncan; Diogo Mosqueira; Maria Barbadillo Munoz; Nguyen T N Vo; Chris Denning
Journal:  Stem Cells Dev       Date:  2018-03-12       Impact factor: 3.272

Review 3.  From iPSC towards cardiac tissue-a road under construction.

Authors:  Stefan Peischard; Ilaria Piccini; Nathalie Strutz-Seebohm; Boris Greber; Guiscard Seebohm
Journal:  Pflugers Arch       Date:  2017-06-01       Impact factor: 3.657

4.  Adrenergic Stress Protection of Human iPS Cell-Derived Cardiomyocytes by Fast Kv7.1 Recycling.

Authors:  Ilaria Piccini; Edda Fehrmann; Stefan Frank; Frank U Müller; Boris Greber; Guiscard Seebohm
Journal:  Front Physiol       Date:  2017-09-14       Impact factor: 4.566

5.  Large-Scale Simulation of the Phenotypical Variability Induced by Loss-of-Function Long QT Mutations in Human Induced Pluripotent Stem Cell Cardiomyocytes.

Authors:  Michelangelo Paci; Simona Casini; Milena Bellin; Jari Hyttinen; Stefano Severi
Journal:  Int J Mol Sci       Date:  2018-11-13       Impact factor: 5.923

6.  Investigating the Complex Arrhythmic Phenotype Caused by the Gain-of-Function Mutation KCNQ1-G229D.

Authors:  Xin Zhou; Alfonso Bueno-Orovio; Richard J Schilling; Claire Kirkby; Chris Denning; Divya Rajamohan; Kevin Burrage; Andrew Tinker; Blanca Rodriguez; Stephen C Harmer
Journal:  Front Physiol       Date:  2019-03-18       Impact factor: 4.566

7.  Cardiomyocytes from human pluripotent stem cells: From laboratory curiosity to industrial biomedical platform.

Authors:  Chris Denning; Viola Borgdorff; James Crutchley; Karl S A Firth; Vinoj George; Spandan Kalra; Alexander Kondrashov; Minh Duc Hoang; Diogo Mosqueira; Asha Patel; Ljupcho Prodanov; Divya Rajamohan; William C Skarnes; James G W Smith; Lorraine E Young
Journal:  Biochim Biophys Acta       Date:  2015-10-31

8.  Drug-Mediated Shortening of Action Potentials in LQTS2 Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Authors:  Gary Duncan; Karl Firth; Vinoj George; Minh Duc Hoang; Andrew Staniforth; Godfrey Smith; Chris Denning
Journal:  Stem Cells Dev       Date:  2017-10-09       Impact factor: 3.272
  8 in total

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