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Literature DB >> 25795241

Reply to Christ et al.: LQT1 and JLNS phenotypes in hiPSC-derived cardiomyocytes are due to KCNQ1 mutations.

Boris Greber¹, Arie O Verkerk², Guiscard Seebohm³, Christine L Mummery⁴, Milena Bellin⁵.

Abstract

Entities: Gene

Mesh：

Substances：
KCNQ1 Potassium Channel

Year: 2015 PMID： 25795241 PMCID： PMC4413298 DOI： 10.1073/pnas.1503762112

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

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5 in total

1. LQT1-phenotypes in hiPSC: Are we measuring the right thing?

Authors: Torsten Christ; András Horvath; Thomas Eschenhagen
Journal: Proc Natl Acad Sci U S A Date: 2015-03-20 Impact factor: 11.205

2. Biophysical properties of slow potassium channels in human embryonic stem cell derived cardiomyocytes implicate subunit stoichiometry.

Authors: Kai Wang; Cecile Terrenoire; Kevin J Sampson; Vivek Iyer; Jeremiah D Osteen; Jonathan Lu; Gordon Keller; Darrell N Kotton; Robert S Kass
Journal: J Physiol Date: 2011-10-24 Impact factor: 5.182

3. Patient-specific induced pluripotent stem-cell models for long-QT syndrome.

Authors: Alessandra Moretti; Milena Bellin; Andrea Welling; Christian Billy Jung; Jason T Lam; Lorenz Bott-Flügel; Tatjana Dorn; Alexander Goedel; Christian Höhnke; Franz Hofmann; Melchior Seyfarth; Daniel Sinnecker; Albert Schömig; Karl-Ludwig Laugwitz
Journal: N Engl J Med Date: 2010-07-21 Impact factor: 91.245

Review 4. Blockade of the I(Ks) potassium channel: an overlooked cardiovascular liability in drug safety screening?

Authors: Rob Towart; Joannes T M Linders; An N Hermans; Jutta Rohrbacher; Henk J van der Linde; Martine Ercken; Miroslav Cik; Peter Roevens; Ard Teisman; David J Gallacher
Journal: J Pharmacol Toxicol Methods Date: 2009-05-09 Impact factor: 1.950

5. Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue.

Authors: Miao Zhang; Cristina D'Aniello; Arie O Verkerk; Eva Wrobel; Stefan Frank; Dorien Ward-van Oostwaard; Ilaria Piccini; Christian Freund; Jyoti Rao; Guiscard Seebohm; Douwe E Atsma; Eric Schulze-Bahr; Christine L Mummery; Boris Greber; Milena Bellin
Journal: Proc Natl Acad Sci U S A Date: 2014-12-01 Impact factor: 11.205

5 in total

4 in total

Reply to Christ et al.: LQT1 and JLNS phenotypes in hiPSC-derived cardiomyocytes are due to KCNQ1 mutations.

1. LQT1-phenotypes in hiPSC: Are we measuring the right thing?

2. Biophysical properties of slow potassium channels in human embryonic stem cell derived cardiomyocytes implicate subunit stoichiometry.

3. Patient-specific induced pluripotent stem-cell models for long-QT syndrome.

Review 4. Blockade of the I(Ks) potassium channel: an overlooked cardiovascular liability in drug safety screening?

5. Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue.

1. Simplified Footprint-Free Cas9/CRISPR Editing of Cardiac-Associated Genes in Human Pluripotent Stem Cells.

Review 2. From iPSC towards cardiac tissue-a road under construction.

3. Adrenergic Stress Protection of Human iPS Cell-Derived Cardiomyocytes by Fast K_v7.1 Recycling.

4. Drug-Mediated Shortening of Action Potentials in LQTS2 Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.