Literature DB >> 25794824

Endoplasmic reticulum quality control in cancer: Friend or foe.

Hana Kim1, Asmita Bhattacharya2, Ling Qi3.   

Abstract

Quality control systems in the endoplasmic reticulum (ER) mediated by unfolded protein response (UPR) and endoplasmic reticulum associated degradation (ERAD) ensure cellular function and organismal survival. Recent studies have suggested that ER quality-control systems in cancer cells may serve as a double-edged sword that aids progression as well as prevention of tumor growth in a context-dependent manner. Here we review recent advances in our understanding of the complex relationship between ER proteostasis and cancer pathology, with a focus on the two most conserved ER quality-control mechanisms--the IRE1α-XBP1 pathway of the UPR and SEL1L-HRD1 complex of the ERAD.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  ERAD; IRE1α-XBP1; Protein folding; SEL1L–HRD1; UPR

Mesh：

Substances：

Year:  2015        PMID： 25794824      PMCID： PMC4523434          DOI： 10.1016/j.semcancer.2015.02.003

Source DB:  PubMed          Journal:  Semin Cancer Biol        ISSN： 1044-579X            Impact factor:   15.707


  98 in total

1.  Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion.

Authors:  Ann-Hwee Lee; Keely Heidtman; Gökhan S Hotamisligil; Laurie H Glimcher
Journal:  Proc Natl Acad Sci U S A       Date:  2011-05-09       Impact factor: 11.205

2.  Deficiency of suppressor enhancer Lin12 1 like (SEL1L) in mice leads to systemic endoplasmic reticulum stress and embryonic lethality.

Authors:  Adam B Francisco; Rajni Singh; Shuai Li; Anish K Vani; Liu Yang; Robert J Munroe; Giuseppe Diaferia; Marina Cardano; Ida Biunno; Ling Qi; John C Schimenti; Qiaoming Long
Journal:  J Biol Chem       Date:  2010-03-02       Impact factor: 5.157

3.  SEL1L, an UPR response protein, a potential marker of colonic cell transformation.

Authors:  Hassan Ashktorab; William Green; Giovanna Finzi; Fausto Sessa; Mehdi Nouraie; Edward L Lee; Annalisa Morgano; Antonio Moschetta; Monica Cattaneo; Renato Mariani-Costantini; Hassan Brim; Ida Biunno
Journal:  Dig Dis Sci       Date:  2012-02-16       Impact factor: 3.199

4.  SEL1L and squamous cell carcinoma of the esophagus.

Authors:  Paola Granelli; Monica Cattaneo; Stefano Ferrero; Luca Bottiglieri; Silvano Bosari; Giuseppe Fichera; Ida Biunno
Journal:  Clin Cancer Res       Date:  2004-09-01       Impact factor: 12.531

Review 5.  Inside and out: the activities of senescence in cancer.

Authors:  Pedro A Pérez-Mancera; Andrew R J Young; Masashi Narita
Journal:  Nat Rev Cancer       Date:  2014-07-17       Impact factor: 60.716

6.  Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress.

Authors:  Rajarshi Ghosh; Likun Wang; Eric S Wang; B Gayani K Perera; Aeid Igbaria; Shuhei Morita; Kris Prado; Maike Thamsen; Deborah Caswell; Hector Macias; Kurt F Weiberth; Micah J Gliedt; Marcel V Alavi; Sanjay B Hari; Arinjay K Mitra; Barun Bhhatarai; Stephan C Schürer; Erik L Snapp; Douglas B Gould; Michael S German; Bradley J Backes; Dustin J Maly; Scott A Oakes; Feroz R Papa
Journal:  Cell       Date:  2014-07-10       Impact factor: 41.582

7.  Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability.

Authors:  Takao Iwawaki; Ryoko Akai; Shinya Yamanaka; Kenji Kohno
Journal:  Proc Natl Acad Sci U S A       Date:  2009-09-15       Impact factor: 11.205

8.  Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase.

Authors:  J S Cox; C E Shamu; P Walter
Journal:  Cell       Date:  1993-06-18       Impact factor: 41.582

9.  Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells.

Authors:  Wenwen Chien; Ling-Wen Ding; Qiao-Yang Sun; Lucia A Torres-Fernandez; Siew Zhuan Tan; Jinfen Xiao; Su Lin Lim; Manoj Garg; Kian Leong Lee; Shojiro Kitajima; Sumiko Takao; Wei Zhong Leong; Haibo Sun; Itay Tokatly; Lorenz Poellinger; Sigal Gery; Phillip H Koeffler
Journal:  Oncotarget       Date:  2014-07-15

10.  ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells.

Authors:  Lukas Niederreiter; Teresa M J Fritz; Timon E Adolph; Anna-Maria Krismer; Felix A Offner; Markus Tschurtschenthaler; Magdalena B Flak; Shuhei Hosomi; Michal F Tomczak; Nicole C Kaneider; Edina Sarcevic; Sarah L Kempster; Tim Raine; Daniela Esser; Philip Rosenstiel; Kenji Kohno; Takao Iwawaki; Herbert Tilg; Richard S Blumberg; Arthur Kaser
Journal:  J Exp Med       Date:  2013-09-16       Impact factor: 14.307
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  33 in total

1.  A H(a)rd Way to Adapt in Cardiac Hypertrophy.

Authors:  Haipeng Sun; Chen Gao; Yibin Wang
Journal:  Circ Res       Date:  2015-08-28       Impact factor: 17.367

2.  Characterising cis-regulatory variation in the transcriptome of histologically normal and tumour-derived pancreatic tissues.

Authors:  Mingfeng Zhang; Soren Lykke-Andersen; Bin Zhu; Wenming Xiao; Jason W Hoskins; Xijun Zhang; Lauren M Rost; Irene Collins; Martijn van de Bunt; Jinping Jia; Hemang Parikh; Tongwu Zhang; Lei Song; Ashley Jermusyk; Charles C Chung; Bin Zhu; Weiyin Zhou; Gail L Matters; Robert C Kurtz; Meredith Yeager; Torben Heick Jensen; Kevin M Brown; Halit Ongen; William R Bamlet; Bradley A Murray; Mark I McCarthy; Stephen J Chanock; Nilanjan Chatterjee; Brian M Wolpin; Jill P Smith; Sara H Olson; Gloria M Petersen; Jianxin Shi; Laufey Amundadottir
Journal:  Gut       Date:  2017-06-20       Impact factor: 23.059

3.  Compensatory increases of select proteostasis networks after Hsp70 inhibition in cancer cells.

Authors:  Sara Sannino; Christopher J Guerriero; Amit J Sabnis; Donna Beer Stolz; Callen T Wallace; Peter Wipf; Simon C Watkins; Trever G Bivona; Jeffrey L Brodsky
Journal:  J Cell Sci       Date:  2018-09-05       Impact factor: 5.285

4.  Aberrant expression of Sec61α in esophageal cancers.

Authors:  Kai Bachmann; Maximillian Bockhorn; Oliver Mann; Florian Gebauer; Marco Blessmann; Jakob Robert Izbicki; Katharina Grupp
Journal:  J Cancer Res Clin Oncol       Date:  2019-06-13       Impact factor: 4.553

Review 5.  Cancer and Alzheimer's disease inverse relationship: an age-associated diverging derailment of shared pathways.

Authors:  Cristina Lanni; Mirco Masi; Marco Racchi; Stefano Govoni
Journal:  Mol Psychiatry       Date:  2020-05-07       Impact factor: 15.992

Review 6.  New Insights into the Physiological Role of Endoplasmic Reticulum-Associated Degradation.

Authors:  Ling Qi; Billy Tsai; Peter Arvan
Journal:  Trends Cell Biol       Date:  2017-02-09       Impact factor: 20.808

7.  Transcription factor c-Myb: novel prognostic factor in osteosarcoma.

Authors:  Kamila Říhová; Monika Dúcka; Iva Staniczková Zambo; Ladislava Vymětalová; Martin Šrámek; Filip Trčka; Jan Verner; Stanislav Drápela; Radek Fedr; Tereza Suchánková; Barbora Pavlatovská; Eva Ondroušková; Irena Kubelková; Danica Zapletalová; Štěpán Tuček; Peter Múdry; Dagmar Adámková Krákorová; Lucia Knopfová; Jan Šmarda; Karel Souček; Lubor Borsig; Petr Beneš
Journal:  Clin Exp Metastasis       Date:  2022-01-07       Impact factor: 5.150

Review 8.  Emerging tale of UPR and cancer: an essentiality for malignancy.

Authors:  Younis Mohammad Hazari; Arif Bashir; Ehtisham Ul Haq; Khalid Majid Fazili
Journal:  Tumour Biol       Date:  2016-09-14

9.  Unique integrated stress response sensors regulate cancer cell susceptibility when Hsp70 activity is compromised.

Authors:  Sara Sannino; Megan E Yates; Mark E Schurdak; Steffi Oesterreich; Adrian V Lee; Peter Wipf; Jeffrey L Brodsky
Journal:  Elife       Date:  2021-06-28       Impact factor: 8.140

10.  Endoplasmic reticulum-associated degradation regulates mitochondrial dynamics in brown adipocytes.

Authors:  Zhangsen Zhou; Mauricio Torres; Haibo Sha; Christopher J Halbrook; Françoise Van den Bergh; Rachel B Reinert; Tatsuya Yamada; Siwen Wang; Yingying Luo; Allen H Hunter; Chunqing Wang; Thomas H Sanderson; Meilian Liu; Aaron Taylor; Hiromi Sesaki; Costas A Lyssiotis; Jun Wu; Sander Kersten; Daniel A Beard; Ling Qi
Journal:  Science       Date:  2020-03-19       Impact factor: 47.728
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