Literature DB >> 25794791

Recent advances in the chemistry and biology of pyridopyrimidines.

F Buron1, J Y Mérour1, M Akssira2, G Guillaumet1, S Routier3.   

Abstract

The interest in pyridopyrimidine cores for pharmaceutical products makes this scaffold a highly useful building block for organic chemistry. These derivatives have found applications in various areas of medicine such as anticancer, CNS, fungicidal, antiviral, anti-inflammatory, antimicrobial, and antibacterial therapies. This review mainly focuses on the progress achieved since 2004 in the chemistry and biological activity of pyridopyrimidines.
Copyright © 2015 Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  Heterocycles; Pharmacological activities; Pyridopyrimidine; Synthesis

Mesh：

Substances：

Year:  2015        PMID： 25794791     DOI： 10.1016/j.ejmech.2015.03.029

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN： 0223-5234            Impact factor:   6.514


  7 in total

1.  One pot synthesis, antimicrobial and antioxidant activities of fused uracils: pyrimidodiazepines, lumazines, triazolouracil and xanthines.

Authors:  Samar A El-Kalyoubi; Eman A Fayed; Ahmed S Abdel-Razek
Journal:  Chem Cent J       Date:  2017-07-19       Impact factor: 4.215

2.  Steroidal[17,16-d]pyrimidines derived from dehydroepiandrosterone: A convenient synthesis, antiproliferation activity, structure-activity relationships, and role of heterocyclic moiety.

Authors:  Shaoyong Ke; Liqiao Shi; Zhigang Zhang; Ziwen Yang
Journal:  Sci Rep       Date:  2017-03-14       Impact factor: 4.379

Review 3.  Pyrido[2,3-d]pyrimidin-7(8H)-ones: Synthesis and Biomedical Applications.

Authors:  Guillem Jubete; Raimon Puig de la Bellacasa; Roger Estrada-Tejedor; Jordi Teixidó; José I Borrell
Journal:  Molecules       Date:  2019-11-16       Impact factor: 4.411

Review 4.  Microwave-assisted multicomponent reactions in heterocyclic chemistry and mechanistic aspects.

Authors:  Shivani Gulati; Stephy Elza John; Nagula Shankaraiah
Journal:  Beilstein J Org Chem       Date:  2021-04-19       Impact factor: 2.883

5.  Aminations and arylations by direct C-O activation for the design of 7,8-dihydro-6H-5,8-ethanopyrido[3,2-d]pyrimidines.

Authors:  Mazarine Laurent; Stéphane Bostyn; Mathieu Marchivie; Yves Robin; Sylvain Routier; Frédéric Buron
Journal:  RSC Adv       Date:  2021-05-28       Impact factor: 4.036

6.  Regioselective Synthesis of New 2,4-(Het)aryl-3H-pyrido[1',2':1,5]pyrazolo[4,3-d]pyrimidines Involving Palladium-Catalyzed Cross-Coupling Reactions.

Authors:  Abdelaziz Ejjoummany; Rabia Belaroussi; Ahmed El Hakmaoui; Mohamed Akssira; Gérald Guillaumet; Frédéric Buron; Sylvain Routier
Journal:  Molecules       Date:  2018-10-23       Impact factor: 4.411

Review 7.  Review on the Synthesis and Therapeutic Potential of Pyrido[2,3-d], [3,2-d], [3,4-d] and [4,3-d]pyrimidine Derivatives.

Authors:  Joana F Campos; Thierry Besson; Sabine Berteina-Raboin
Journal:  Pharmaceuticals (Basel)       Date:  2022-03-14
  7 in total

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