Ryo Tanaka1, Junya Ozawa1, Nobuhiro Kito1, Takahiro Yamasaki1, Hideki Moriyama2. 1. Department of Integrated Rehabilitation, Hiroshima International University, Japan. 2. Department of Rehabilitation Science, Kobe University Graduate School of Health Sciences, Japan.
Abstract
PURPOSE: To investigate improvement in various impairments by exercise interventions in patients with knee osteoarthritis (OA). METHODS: We collected data on randomized controlled trials (RCTs) comparing the effects of exercise intervention with those of either nonintervention or psychoeducational intervention in patients with knee OA. Data on pain, stiffness, muscle strength, range of motion, flexibility, maximal oxygen uptake, and position sense were synthesized. The Grading of Recommendations Assessment, Development, and Evaluation system was used to determine the quality of the evidence. RESULTS: Thirty-three RCTs involving 3,192 participants were identified. Meta-analysis provided highquality evidence that exercise intervention improves maximal oxygen uptake, and moderate-quality evidence that exercise intervention also improves pain, stiffness, knee extensor and flexor muscle strength, and position sense. The evidence that exercise intervention improves knee extension and flexion range of motion was deemed as undetermined-quality. CONCLUSION: In patients with knee OA, improvement in pain, stiffness, muscle strength, maximal oxygen uptake, and position sense with the use of exercise intervention can be expected. Although the quality of evidence of the effect of exercise intervention on range of motion was inconclusive, exercise intervention should be recommended for patients with knee OA to improve various impairments.
PURPOSE: To investigate improvement in various impairments by exercise interventions in patients with knee osteoarthritis (OA). METHODS: We collected data on randomized controlled trials (RCTs) comparing the effects of exercise intervention with those of either nonintervention or psychoeducational intervention in patients with knee OA. Data on pain, stiffness, muscle strength, range of motion, flexibility, maximal oxygen uptake, and position sense were synthesized. The Grading of Recommendations Assessment, Development, and Evaluation system was used to determine the quality of the evidence. RESULTS: Thirty-three RCTs involving 3,192 participants were identified. Meta-analysis provided highquality evidence that exercise intervention improves maximal oxygen uptake, and moderate-quality evidence that exercise intervention also improves pain, stiffness, knee extensor and flexor muscle strength, and position sense. The evidence that exercise intervention improves knee extension and flexion range of motion was deemed as undetermined-quality. CONCLUSION: In patients with knee OA, improvement in pain, stiffness, muscle strength, maximal oxygen uptake, and position sense with the use of exercise intervention can be expected. Although the quality of evidence of the effect of exercise intervention on range of motion was inconclusive, exercise intervention should be recommended for patients with knee OA to improve various impairments.
Authors: Stephen P Messier; Richard F Loeser; Gary D Miller; Timothy M Morgan; W Jack Rejeski; Mary Ann Sevick; Walter H Ettinger; Marco Pahor; Jeff D Williamson Journal: Arthritis Rheum Date: 2004-05
Authors: Adam Perlman; Susan Gould Fogerite; Oliver Glass; Elizabeth Bechard; Ather Ali; Valentine Y Njike; Carl Pieper; Natalia O Dmitrieva; Alison Luciano; Lisa Rosenberger; Teresa Keever; Carl Milak; Eric A Finkelstein; Gwendolyn Mahon; Giovanni Campanile; Ann Cotter; David L Katz Journal: J Gen Intern Med Date: 2018-12-12 Impact factor: 5.128