Literature DB >> 2579175

Quantitative analysis of alkaline phosphatases in serum and amniotic fluid: comparison of biochemical and immunologic assays.

R A Mulivor, D Boccelli, H Harris.   

Abstract

An immunoprecipitation method using monoclonal antibodies specific for the three categories of alkaline phosphatases, liver/bone/kidney, placental, and intestinal, is described and compared with the heat denaturation-chemical inhibition method for quantitating the contributions of the various isoenzymes to the total activity in biologic fluids. Activity values for the three categories of isoenzymes present in normal and pregnancy sera as well as in early gestation amniotic fluids were determined by both methods. There is very close correlation between the values obtained by both methods. Thus, two independent procedures are now available for quantitating the contributions of the various alkaline phosphatase isoenzymes in biologic fluids.

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Substances：

Year:  1985        PMID： 2579175

Source DB:  PubMed          Journal:  J Lab Clin Med        ISSN： 0022-2143


  8 in total

1.  Characterization of the phosphatidylinositol-glycan membrane anchor of human placental alkaline phosphatase.

Authors:  A D Howard; J Berger; L Gerber; P Familletti; S Udenfriend
Journal:  Proc Natl Acad Sci U S A       Date:  1987-09       Impact factor: 11.205

2.  Prenatal diagnosis of cystic fibrosis using linked DNA markers and microvillar intestinal enzyme analysis.

Authors:  J E Spence; G J Buffone; C L Rosenbloom; S D Fernbach; M R Curry; R J Carpenter; D H Ledbetter; W E O'Brien; A L Beaudet
Journal:  Hum Genet       Date:  1987-05       Impact factor: 4.132

3.  Prenatal diagnosis in 200 pregnancies with a 1-in-4 risk of cystic fibrosis.

Authors:  A Boué; F Muller; C Nezelof; J F Oury; F Duchatel; Y Dumez; M C Aubry; J Boué
Journal:  Hum Genet       Date:  1986-11       Impact factor: 4.132

4.  Analysis of fetal intestinal enzymes in amniotic fluid for the prenatal diagnosis of cystic fibrosis.

Authors:  R A Mulivor; D Cook; F Muller; A Boué; F Gilbert; M Mennuti; E Pergament; M Potier; H Nadler; H Punnett
Journal:  Am J Hum Genet       Date:  1987-02       Impact factor: 11.025

5.  Alkaline phosphatase (tissue-nonspecific isoenzyme) is a phosphoethanolamine and pyridoxal-5'-phosphate ectophosphatase: normal and hypophosphatasia fibroblast study.

Authors:  K N Fedde; M P Whyte
Journal:  Am J Hum Genet       Date:  1990-11       Impact factor: 11.025

6.  Alkaline phosphatase: placental and tissue-nonspecific isoenzymes hydrolyze phosphoethanolamine, inorganic pyrophosphate, and pyridoxal 5'-phosphate. Substrate accumulation in carriers of hypophosphatasia corrects during pregnancy.

Authors:  M P Whyte; M Landt; L M Ryan; R A Mulivor; P S Henthorn; K N Fedde; J D Mahuren; S P Coburn
Journal:  J Clin Invest       Date:  1995-04       Impact factor: 14.808

7.  A missense mutation in the human liver/bone/kidney alkaline phosphatase gene causing a lethal form of hypophosphatasia.

Authors:  M J Weiss; D E Cole; K Ray; M P Whyte; M A Lafferty; R A Mulivor; H Harris
Journal:  Proc Natl Acad Sci U S A       Date:  1988-10       Impact factor: 11.205

8.  Impact of occupational health hazards on serum markers of bone formation in spray painters of Chennai region in Tamil Nadu.

Authors:  Vijaya Prakash Krishnan Muthaiah; Abel Arul Nathan; Anandan Balakrishnan; Rajiv Rose; Jayaraman Gopalsamy
Journal:  Indian J Occup Environ Med       Date:  2012-05
  8 in total

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